Vol - 25, Issue - 3
About the Journal
[This article belongs to Volume - 25, Issue - 3]
International Medical Journal
Journal ID : IMJ-01-03-2020-311
Total View : 137

Abstract : Over many years, different areas of cancer biology are explored to find a cure for cancer. The immune system, acting via cancer immune-surveillance, is considered a potential target for improving outcomes among some malignancies. The improved ability to harness, engineer and educate immune cells to target cancer cells has changed the paradigm for treating. Only a few studies every year have succeeded to provide a regimen significantly improving the survival of cancer patients. There was an urgency to search for other versatile and bright approaches for a more effective fight against cancer. The benefit field to achievement appeared to be immunotherapy that enhances the patients’ own immunological system by equipping its immunocompetent cells with further functions to independently combat malignant cells. FDA-approved chimeric antigen receptor (CAR) T cell therapy that uses a patient’s immune system to fight certain hematologic cancers. Additionally, research is ongoing to evaluate CAR T therapy for patients with solid tumors of the breast, prostate, brain, lungs and other organs

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