Vol - 28, Issue - 04
About the Journal
[This article belongs to Volume - 28, Issue - 04]
International Medical Journal
Journal ID : IMJ-04-04-2021-823
Total View : 385

Abstract : A wound infection is a result of a complex interplay of many factors. Once the integrity of the skin and its protective function is compromised, large quantities of foreign antigens can enter the wound and cause an inflammatory response. Surgeons nowadays have widely been using antimicrobial agents as prophylaxis to reduce the incidence of postoperative infection and associated morbidity. The objective of preoperative antibiotic prophylaxis is largely aimed at preventing infections in the postoperative period. The use of intra-incisional infiltration of prophylactic antibiotic along the incisional site is one such method to prevent surgical site infections. In this study we randomly divided 100 patients in two groups and tested the efficacy of intraincisional instillation of injectable antibiotics to prevent surgical site infection. The incidence of surgical site infection (SSI) is found to be 4% in Group A where both intraincisional and intravenous antibiotic prophylaxis was given and 16% in Group B where only intravenous antibiotic prophylaxis was given. This concludes that the use of intraincisional instillation of injectable antibiotic at the site of incision along with intravenous antibiotic prophylaxis helps in avoiding postoperative surgical site infection (SSI). The most common organism which was isolated from wounds with surgical site infection was methicillin-sensitive Staphylococcus aureus. Escherichia coli being the second most common organism isolated on culture. When compared the use of intraincisional infiltration of antibiotics along with intravenous prophylaxis is more efficacious in preventing SSI than using only intravenous antibiotic prophylaxis in cases of appendectomy.

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