Vol - 28, Issue - 04
About the Journal
[This article belongs to Volume - 28, Issue - 04]
International Medical Journal
Journal ID : IMJ-01-04-2021-820
Total View : 354

Abstract : Intrathecal administration of fentanyl has been clinically proven to prolong period of analgesia and hence it is the most common adjuvant used. Nalbuphine is another opioid that can be used as an adjuvant to local anesthetics. Our prospective randomized double blinded comparative study aimed to compare the efficacy of addition of Nalbuphine and Fentanyl to Hyperbaric 0.5% Bupivacaine intrathecally. First group, were given 3 ml of 0.5% hyperbaric bupivacaine with 0.8 mg of Nalbuphine. The other group was given 3ml of 0.5% hyperbaric bupivacaine with 0.5ml (25 mcg) of Fentanyl intrathecally. The onset of the sensory block of Fentanyl group had faster onset as compared to Nalbuphine group with p value < 0.002. Fentanyl group had the faster onset of peak sensory block as compared to Nalbuphine group with p value of 0.004. Fentanyl group had the faster onset of complete motor block (7.3 ± 1.04 mins) with p value of < 0.001. Nalbuphine group took the longest time for two segment regression (130.52 ± 26.4 mins) with p value of < 0.001. The “Visual Analogue Scale” was lower in the nalbuphine group at all-time intervals with statistical significance. The scores showed better postoperative analgesia in the Nalbuphine group.

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