International Medical Journal

Journal ID : IMJ-11-01-2021-720

Total View : 434

Title : DHA-Rich Fish Oil And Tualang Honey Reduce Stress-Induced Oxidative Damage In The Brain

Abstract : Exposure to chronic stress induces oxidative damage which alters the dynamic balance between antioxidant and pro-oxidant activities in the brain. Tualang honey (TH) is a Malaysian wild multifloral honey which has been shown to contain high amount antioxidants. DHA-rich fish oil is a form of omega-3 fatty acid found in fish which also possesses some antioxidant activity. This study aimed to evaluate anti-stress activity of DHA-rich fish oil, TH and their combination on several parameters of oxidative stress in the brain. Fifty male Sprague Dawley rats were divided into (i) control, (ii) stress-exposed, (iii) stress-exposed and treated with TH (1 g/kg body weight twice daily), (iv) stress-exposed and treated with DHA-rich fish oil (450 mg/kg body weight twice daily), and (v) stress-exposed and treated with a combination of TH and DHA-rich fish oil. The chronic stress regimen consisted of a combination of restraint stress and a swim stress test for 28 days. DHA-rich fish oil and TH significantly (p < 0.05) supressed stress-induced elevation of serum corticosterone and lipid peroxidation and caused significant increase in total antioxidant capacity. For glutathione status, only TH significantly reduced stress-induced elevation of oxidised glutathione (GSSG) and normalised GSH/GSSG ratio. Both DHA-rich fish oil and TH have protective effects against brain oxidative stress but consuming these substances together does not seem to provide an additional benefit compared to consuming them separately..
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International Medical Journal

Journal ID : IMJ-08-01-2021-716

Total View : 433

Title : Hyperglycemia Induced by COVID-19 with and without present Diabetes: A Systematic Review

Abstract : COVID-19 is a major emerging disease that affects any certain condition. However, a recent report suggests the occurrence of hyperglycemia without any present diabetes in COVID-19 patients. This study aimed to systematically review recent evidence on hyperglycemia in COVID-19 patients. Literature research was done using four search engines, consist of Google Scholar, Pubmed, Science Direct, and ProQuest, and limited to English manuscript only and published in the last 1 year. SARS-CoV-2 could damage the pancreas by causing the destruction of the β-cell structure that leads to impairment of glucose metabolism and worsen pre-existing diabetes or determine the appearance of hyperglycemia in non-diabetes. Inflammation also plays a major important role in hyperglycemia related to COVID-19. Hyperglycemia increased the vulnerability of the lung, by promoting and facilitating the entry of the SARS-CoV-2 into the host cells, and decreasing lung function. Moreover, the mortality and morbidity rate conceivable increased due to hyperglycemia. The presence of high glucose levels is linked with the progression of COVID-19 severity. Thus, the glucose level should be concerned, either in a patient with present diabetes or without any presence of diabetes. Examination and monitoring of glucose levels might be a useful tool to prevent the seriousness of COVID-19..
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International Medical Journal

Journal ID : IMJ-08-01-2021-715

Total View : 468

Title : THE CORONA VIRUS OUTBREAK AND ADMISSION TRENDS IN A MULTISPECIALITY HOSPITAL OF PATIENTS ADMITTED IN CARDIOLOGY DEPARTMENT: A COMPARATIVE STUDY WITH DATA FROM PREVIOUS YEARS

Abstract : A comparison study that analyse the trends in hospital admissions in a tertiary care centre for cardiac services in 2020 during the 1st of March to 31st of May with the data from previous years during the corresponding months. Data extracted from electronic medical records (EMR). For each EMR entry with an admission under the Department of Adult Cardiology, the following information was collected patient demographics and admitting diagnosis. Records were sorted by admitting diagnosis and the number of admissions per patient. When compared with the previous years, admissions for cardiac emergencies like Myocardial infarction were relatively the same in 2020. But there was a statistical reduction in admission (P 0.002) that does not warrant urgent intervention..
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International Medical Journal

Journal ID : IMJ-07-01-2021-714

Total View : 430

Title : THE ROLE AND IMPACT OF RELIGION ON THE HEALTH OF ZIMBABWE’S POPULATION

Abstract :

There are many religions in Zimbabwe. To date a lot of research about Christianity and African Traditional Religion has been done. The research has touched various fields such as history, classification of churches, missionaries, traditional medicine and many more. [7], [2], [13], [3] and many more have covered religion and health in their various ways. This review will reveal the relationship between the health of Zimbabwe population and religion. If a relationship is established, to what degree does it impact the health of Zimbabwe population. This review will outline the healing methods offered by Christianity and African Traditional Religion in Zimbabwe. This review will also reveal the various practices by Christianity and African Traditional Religion which are hazardous to the health of Zimbabwe population. The main aim to reveal the role and impact of religion on the health of Zimbabwe population. Method of research will be in-depth search of articles on Google scholar and Elsevier. Then analysis of information from articles will produce results. Lastly conclusion will be drawn from the results.

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International Medical Journal

Journal ID : IMJ-03-01-2021-712

Total View : 450

Title : A Histopathological Analysis of Granulomatous Lesions of Skin and its Clinical Correlation

Abstract : Granulomatous dermatoses are group of cutaneous lesions occurring as a type IV hypersensitivity reaction against poorly soluble reactive external or internal antigen which can have infectious or non-infectious etiology. They have overlapping features due to which the diagnoses prove to be a challenge for clinicians and pathologists. Hence, the accurate diagnosis is made from adequate clinical information combined with histopathology. The aim was to study the spectrum of granulomatous lesions of skin and to analyze the clinico-pathological correlation. A cross- sectional study of 2 years was conducted on 125 cases of skin biopsies histopathological diagnosed with leprosy. Adequate clinical history was obtained and biopsies were stained with hematoxylin and eosin along with special stains, wherever required. Total 538 skin biopsies were received out of which 125 were diagnosed as granulomatous lesions of skin. Maximum cases (31.20%) belonged to third decade of life with male to female ratio of 1.45:1. On histopathology, tuberculoid granuloma was the most common type. Majority cases were of infectious etiology with predominance of leprosy followed by tuberculosis. Overall leprosy and cutaneous TB showed a good clinic pathological agreement of 93.60% and 96.80%, respectively using Open Epi diagnostic test. Granulomatous skin lesions still pose a diagnostic challenge which raises the concern about therapeutic approaches and various health programmers. They may not have a classical clinical picture always. Hence, histopathological examination of the skin lesion along with proper clinical history and correlation of these findings help in arriving at an accurate diagnosis..
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International Medical Journal

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Submission Deadline ( Vol 30 , Issue 06 )
20 Jun 2023

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Publish On ( Vol 30 , Issue 05 )
31 May 2023