International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-15-06-2020-505
Total View : 292

Abstract : Inguinal hernia surgery is one of the most common elective procedures performed by the surgeons and has evolved from open to laparoscopic technique. This prospective study was conducted to find out intra-operative incidents and post-operative outcomes in patients undergoing TEP and TAPP for inguinal hernia repair. A prospective study was conducted on 50 adult patients who underwent laparoscopic inguinal hernia repair between November 2017 to November 2018. It was a randomised study and equal number of patients were allocated to TAPP and TEP group based on surgeon’s preference. Operative time [p<0.0001], intensity of pain (VAS) was significantly higher in TAPP compared to TEP in the immediate post-operative period (6 hours) and during hospital stay [p=0.0299]. No significant difference observed in VAS between TEP and TAPP during follow up [after 1 week (p=0.2298), 2 weeks (p=0.2337), and 4 weeks (p=0.3944)]. Both TEP and TAPP were comparable in terms of Intra-operative and Post-operative complications {seroma [during hospital stay (p=0.1573), after 1 week (p=0.6375), after 2 weeks (p=0.5513)]; haematoma [during hospital stay (p=0.1492), after 1 week (p=0.3125)]} and Conversion (p=0.3125), and Length of hospital stay (p=0.3960). Time to resume normal work [p<0.0001] was significantly more in TAPP than TEP. Although both procedures are safe and efficacious TEP has a definite edge over TAPP taking into consideration the lesser intensity of post-operative pain during hospital stay, shorter duration of surgery and relatively early return to normal work associated with the former procedure. TEP should therefore be regarded as the procedure of choice for inguinal hernia repair.
Full article
International Medical Journal
Journal ID : IMJ-14-06-2020-504
Total View : 331

Abstract : Sex hormone binding globulin (SHBG) and lipoprotein lipase (LPL) play an important role in erectile dysfunction (ED) in overweight men. This study focuses on the study of the rs727428; rs5934505; rs10822184 single nucleotide polymorphisms that determine the predisposition to erectile dysfunction in overweight men, as well as the relation of these polymorphisms with the level of sex hormones in the Kazakh population. A total of 200 men of Kazakh nationality, after consent, have been selected for the study, of which 70 patients with ED IIEF-5 (6-25) and overweight (BMI ≥ 25) and 130 healthy men IIEF-5 (26-30) normal weight (BMI <25). Single nucleotide polymorphisms rs727428 [C / T]; rs5934505 [C / T]; rs10822184 [T / C], were determined by the TaqMan method. Also, levels of SHBG, total testosterone, and serum albumin were measured. The rs 5934505 SNP is associated with ED affected by obesity (p = 0.004) in comparison with the control group. No association of rs5934505 polymorphism with lipid metabolism and sex hormone levels has been detected. The rs727428 polymorphism affects the level of total testosterone (p = 0.001) and albumin (p = 0.03) while the rs10822184 affects the level of LDL (p = 0.01) and triglycerides (p = 0.04). Thus, rs5934505SNP is associated with erectile dysfunction accompanied by overweight in people of the Kazakh population. This study also reveals that rs727428 affects the level of total testosterone in the Kazakh population.
Full article
International Medical Journal
Journal ID : IMJ-10-06-2020-501
Total View : 252

Abstract : Cardiac Rhabdomyomas are the most common benign cardiac tumours of infancy. They are often associated with Tuberous Sclerosis Complex (TSC). Familial TSC has got about 95% penetrance. Being characterized by cutaneous stigmata in the form of facial angiofibromas, adenoma sebaceum and ashleaf macules, they are easily diagnosed in the clinical scenario. Neonatal tuberous sclerosis is not so commonly diagnosed from cutaneous stigmata. Occult TSC can be retrospectively diagnosed based on echocardiographic findings of cardiac rhabdomyomas in infants. This case report is an example of one rare case where maternal and neonatal tuberous sclerosis was diagnosed retrospectively after the diagnosis of fetal cardiac rhabdomyoma on level II ultrasound and subsequent confirmation on echocardiography. Presenly baby is asymptomatic and is planned for conservative management and follow-up.
Full article
International Medical Journal
Journal ID : IMJ-09-06-2020-500
Total View : 328

Abstract : Vitamin D deficiency and mentality dysfunction are common in low Glomerular Filtration Rate GFR in dialysis and non-dialysis patients, low level of vitamin D most lyrelated to hypertension, neurocognetionimperment, muscle weakness, hyperlipidemic, diabetes, and cardiovascular disease. Mentality domains impairment remains undiagnosed and undermanaged in chronic kidney disease CKD patients. The level of vitamin D clinically estimated by scaling the vitamin D status which is determined clinically by measuring the 25(OH)D vitamin level that circulating within body. Levels of vitamin D ranging within 30-80 ng/ml are considered optimum level, vitamin D level which evaluated as a suboptimal is further classified into deficiency and insufficiency where the susceptible to develop CKD at vitamin D deficiency. Low level of vitamin D associated with mentality dysfunction especially in hemodialysis patients but the link is still not completely cleared. Assess mentality domains defectiveness using one validated score: monumental state examination in patients with low GFR, with or without hemodialysis. A total of 63 patients with no dialysis CKD and 68 patients on scheduled hemodialysis have been included in this study in which CKD was defined as GFR<60 ml/min using MDRD equation. Exclusion criteria: <20 years, pregnant women, deaf patients, low education, and CVA patients. Mentality test have been done for all patients (CKD and ESRD) by using monumental state examination test which measures mentality (mentality) functions with a components of orientation, attention, recall, and language with score >24 (out of 30). Vitamin 25(OH) D-level assessed from each subject using enzyme immunoassay method with assay range from 40-110 ng/ml. for dialysis patients 36.8% had different 25(OH) D-level, while 40.2% had insufficient level, and 22.8 had sufficient vitamin D level. Serum level of 25(OH)D-level was significantly lower in patients on dialysis compared with CKD patients. Minimental status examination score was lower significantly in hemodialysis patients compared to non-dialysis patient. There was significant correlation between various mentality domains test (MMs) and vitamin D levels. there was high prevalence of 25 (OH) D deficiencies in patients with low GFR especially on hemodialysis associated with poor mentality domains.
Full article
International Medical Journal
Journal ID : IMJ-09-06-2020-499
Total View : 217

Abstract : intensive treatment of adult patients with acute lymphocytic leukemia in adults (ALL) by Asparaginase(LASP/PEGASP) was significantly improved patient outcomes. However, much less information available about asparaginase use and toxicity in adult in comparison with its effect in pediatric populations. This was retrospective descriptive study for 56 leukemia patients fromNasseriahgovernoratetreated by PEG-ASP according to UKALL XIprotocol, between January 2015 and October 2019. The Hb, WBCs count, Blastocyte percent., Absolute Neutrophil Count ANC, platelet count, survival rate,transplantation, chemotherapy regimen, duration, type of asparginase,phase, time from last ASP, events, presentation, recovery and dose, were considered and evaluated. 56 patients with ALL were retrospectively enrolled in this study at median age of 30 years. Males represented 60.7 % compared to 39.3 % females. The majority of patients 14(93%) were in phase I and the remaining in phase II.The best dose frequency was three doses that were enough for 8 patients (54%).10 of 15 patients (67%) did not undergo a transplant, while the remaining did not have to.Finally, 10 patients (67%) were survived and three of them with weakness.15(25%) of 56 patients were suffered from the following complications:CVST 5(33%), DVT 4(27%), Hyperglycemia 3(20%), and 1(7%) patient appeared with pancreatitis, biochemical pancreatitis, andskin rash. also, those patients presented with: seizure 5(33%), swelling 3(20%), polyurea 2(13%) and 1(7%) patient suffering polydipsia, abdominal pain, vomiting, redness, and pain. PEG-ASP is feasible as part of an intensive multiagent therapeutic regimen for adult with ALL. This regimen appears associated with improved outcomes,but there are differences in overall survival of those patients sufferingcomplications and those don’t.
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