International Medical Journal

Journal ID : IMJ-07-09-2020-601

Total View : 354

Title : Unienzyme with MPS An Unique armamentarium in the management of Functional Dyspepsia (FD)

Abstract : Dyspepsia or functional dyspepsia (FD) is a term often used to describe the abdominal discomfort and commonly used by many clinicians to account the various symptoms frequently observed in majority of patient of gastrointestinal disorder. FD possesses the group of common symptoms which draw the difference other than peptic ulcer disease and may lead to development of metabolic diseases if not treated within a framework. This review article emphasized on the functional dyspepsia and potential features of unique formulation i.e Unienzyme with MPS in the management of unenviable sign and symptoms of functional dyspepsia or non-ulcer dyspepsia.
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International Medical Journal

Journal ID : IMJ-03-09-2020-598

Total View : 349

Title : Microbiological and Antioxidant Activity of Cultivated Jordanian Bay-Leaves

Abstract : Bay or laurel is a natural plant and its leaves are one of the fundamental regularly used cooking spices. The dry bay leaves are used to treat numerous digestive issues with nonvascular and antibacterial marketers. As a result, this examine turned into aimed to assess biological hobby of Jordanian bay leaves for its microbiological hobby in-vitro by way of extraction crucial oils from sparkling and dry leaves. The dried bay leaves have been extracted via hydro- distillation the use of methanol by means of a soxhlet extractor. The extracts had been focused and evaluated for mic assessments against bacillus coagulant, lactobacillus, streptococcus and candida albicans. In addition, bay leaves extracts have been evaluated for antioxidant activity the usage of dpph assay. The minimum inhibitory awareness (mic) confirmed that methanolic- extract of bay leaves has giant effects against bacillus coagulant and lactobacillus, where detectable effects towards other tested microorganism. But, all of bay leaves extracts displayed no consequences on candida albicans, however the methanolic extract displayed the most prominent stage. The oils confirmed true antibacterial interest towards each gram negative and gramtremendous microorganism. The capacity antioxidant pastime of the bay leaves and methanolic extract of seed oil from l. Nobili’s were evaluated to 94. 65(μg/ml) of DPPH ic 50.
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International Medical Journal

Journal ID : IMJ-31-08-2020-595

Total View : 444

Title : The Uncommon Adverse Effect Case: Bevacizumab Associated Fistula on Advanced Stage Colorectal Adenocarsinoma Undergoing Anti-Vascular Endothelial Growth Factor Adjuvant Chemotherapy

Abstract : Bevacizumab is a humanized monoclonal antibody that targets vascular endothelial growth factor and is used in the standard adjuvant chemotherapy regimens to treat metastatic colorectal cancer (CRC). It is the commonest antiangiogenesis agent to treat metastatic CRC. Venous thromboembolism, delayed wound healing, and spontaneous bowel perforation are the adverse events following bevacizumab treatment. According to the timing of Histula growth relative to operation and starting bevacizumab treatment, Histulas are possibly secondary to bevacizumab treatment rather than postoperative complications. We reported, a single uncommon case of bevacizumab related enterocutaneous Histula on 60 years old woman patient whose already been done R0 resection for left side colon cancer 2 years before. Adjuvant chemotherapy already been given 3 weeks after surgery (using FOLFOX 6 regiments). After 1 year follow up, multiple nodul liver metastase were found on Abdominal CT Scan, the treatment was continued with Hirst line anti-angiogenesis regiment (FOLFOX + Bevacizumab) for another 6 months. On the last cycle, low output enterocutaneous Histula was found from the laparotomy scar, the chemotherapy was interrupted for the last cycle. Conservative treatment was done, parenteral nutritions were started and spontaneous Histula healing could achieved after 10 days and no need for surgical intervention. A small, but significant percentage of CRC cases develop Bevacizumab-associated Histulas, which should be detected early and is managed conservatively.
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International Medical Journal

Journal ID : IMJ-26-08-2020-591

Total View : 561

Title : RECOVERY TRIAL AND HYDROXYCHLOROQUINE

Abstract : During the search for treatments for COVID-19, clinical trials for testing hydroxychloroquine were interrupted by the WHO already on May 25, 2020 after publication of a paper in the magazine The Lancet [2] that stated that patients who had received hydroxychloroquine presented mortality rates of 35% due to severe cardiac arrhythmias. This paper was withdrawn thirteen days after its publication because it was questioned by 120 scientists of various nationalities [3], both as regards the data collected and as regards the method, and on June 2, 2020 also eighty Italian medical doctors sent a letter to The Lancet and to the WHO in which they criticized the scientific contents of the paper. [4] Then, on June 3, 2020, Dr. Tedros Adhanom Ghebreyesus, Director-General of the WHO, allowed restart of recruitment of patients in tests regarding hydroxychloroquine in the Solidarity trial. [5] The Recovery trial then became the principal study on which the WHO based its final decision to confirm for all drug agencies suspension of use of hydroxychloroquine for the treatment of COVID-19.
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International Medical Journal

Journal ID : IMJ-26-08-2020-589

Total View : 437

Title : Malaria Challenges in The COVID-19 Era and The Path Forward on Bangladesh Malaria Elimination Intervention

Abstract : Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. It is preventable and curable. In 2018, there were an estimated 228 million cases of malaria worldwide. The estimated number of malaria deaths stood at 405 000 in 2018. Children aged under 5 years are the most vulnerable group affected by malaria; in 2018, they accounted for 67% (272 000) of all malaria deaths worldwide. The WHO African Region carries a disproportionately high share of the global malaria burden. In 2018, the region was home to 93% of malaria cases and 94% of malaria deaths. Total funding for malaria control and elimination reached an estimated US$ 2.7 billion in 2018. Contributions from governments of endemic countries amounted to US$ 900 million, representing 30% of total funding. As the COVID-19 pandemic spreads rapidly around the globe, there is an urgent need to aggressively tackle the novel coronavirus while ensuring that other killer diseases, such as malaria, are not neglected. The WHO Global Malaria Program is leading a cross-partner effort to mitigate the negative impact of the coronavirus in malaria-affected countries and, where possible, contribute towards a successful COVID-19 response. The present review attempts to assess the progress gained in malaria elimination during the past few years and highlights some issues that could be important in successful malaria elimination.
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International Medical Journal

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Submission Deadline ( Vol 30 , Issue 04 )
20 Apr 2023

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Publish On ( Vol 30 , Issue 03 )
31 Mar 2023