International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley Shenyang Jianzhu Daxue Xuebao (Ziran Kexue Ban)/Journal of Shenyang Jianzhu University (Natural Science) General Medicine (ISSN:1311-1817) Chinese Journal of Evidence-Based Medicine Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation Lizi Jiaohuan Yu Xifu/Ion Exchange and Adsorption

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-27-06-2020-522
Total View : 4
Title : THE SAFETY AND EFFICACY OF BOTULINIUM TOXIN IN THE TREATMENT OF ERYTHMATO-TELANGIECTATIC ROSACEA
Abstract : It is challenging to treat flushing and persistent erythema of rosacea in spite of many topical and systemic treatment options. Recently, intradermal botulinum toxin injection has been used as a novel treatment for erythemato- telangiectatic rosacea. This study aims to evaluate the safety and efficacy of intra- dermal injection of Botulinum Toxin A (BTA) as a treatment for erythemato- telangiectactic rosacea ETR. A prospective study was done on patients with ETR treated with intra-dermal injections of BTA. Initial assessment of patients at baseline was documented then assessment of cases after injection was done using the five parameters of ETR severity scoring system The presence of the reported side effects were specifically assessed. A total 21 patients with ETR participated in the study. The mean age was 35.42 ± 9.43 year. The majority of patients (N=17, 81%) were noted to have significant improvement of their rosacea symptoms with treatment, the mean ETR score showed significant decrement from 8.48 to 4.64 over follow up visits with statistical significant (P = 0.001*). The compliance rate was 90%. None of the patients report any major side effects. Intradermal botulinum toxin injection considered a reasonable treatment modality for ETR. it is safe, effective and can provide reliable relief of long-lasting symptom of ETR. The procedure is well tolerated and provide a desirable alternative for daily topical treatments or systemic medications..
Full article
International Medical Journal
Journal ID : IMJ-20-06-2020-520
Total View : 423
Title : Co-Transplantation of Mesenchymal Stem Cells and Hematopoietic Stem Cells for Prevention of Graft-versus-Host Disease
Abstract : GvHD is the main cause of allogeneic stem cell transplant related mortality in both pediatric and adults. GvHD occurs when donor’s T cells do not show tolerance against specific proteins on host cells. There are several methods for prevention and control of GVHD, including corticosteroids (especially prednisolone) as the first line therapeutic approach. But drug resistance to immunosuppressive drugs in some patients on one hand, and infection due to overuse of them on the other hand, has failed this treatment in 30-40% of transplanted patients. It is now believed that substituting preventive methods for GVHD rather than treating it is more reliable. Mesenchymal Stem Cell (MSC) Therapy as a new therapeutic approach has been used for reducing the risk of GvHD. Hematopoietic stem cells (HSCs) were proposed in some previous researches as positive tools in reducing the risk of GvHD. During this study, we first isolated and prepared MSCs and HSCs. The levels of sDNAM1 as a predictor biomarker of GvHD as well as blood levels of ST2, TNFR1, REG3α and sDNAM1 and Treg cell biomarkers of allogeneic transplant patients were evaluated before and after co-transplantation of HSCs and MSCs. According to this study, the co-transplantation of HSCs and MSCs did not show a significant difference compared to the group received MSCs alone.
Full article
International Medical Journal
Journal ID : IMJ-20-06-2020-518
Total View : 356
Title : Correlation of Fibroblast growth factor (FGF23) with progress stages of diabetic nephropathy
Abstract : Diabetic nephropathy is a common complication of diabetes mellitus type2. The mechanism involved is include changes in blood vessel that supply peripheral nerves and metabolic disorder such as increased or activation polyol pathway and non-enzymatic glycation. This study was aimed to Evaluate Fibroblast growth factor 23 (FGF23) in kidney damage susceptibility Correlation of theses markers with disease progression in Diabetic nephropathy patients. This case-control study was carried out on patients who attended multi teaching centers (Baghdad Teaching Hospital and Ghazi Al Harriry Teaching Hospital) for the period from April 2018 to June 2019. The subject which enrolled in this study was 90. The patients were 90 (55 males and 35 females), whose ages ranged from (50 to 82) years. They diagnosed as having CKD and DM based on previous medical reports, laboratory tests and clinical examination by consultant nephrologist. The results of those patients were compared with (30) DM only persons whose ages ranged from (50-82) years (17 males and 13 females), 30 CKD and DM with normal microalbumuria whose ages ranged from (50-82) years (18 males and 12 females), as a control group and 30 DM, CKD and abnormal microalbumuria. The following tests were applied for all the patients and the control groups; they were evaluated by different laboratory methods: Serum fibroblast growth factor 23 Serum urea, Serum creatinine, and Albumin / creatinine ratio. The level of fasting blood sugar (F.BS) show (P<0.05) significance difference among the three groups with the higher level in the DMT2 with macroalbumin compared with the two other groups DMT2 with microalbumin and the DMT2 without albumin nephropathy. Control Correlation tests between FGF23 and (BMI Kg/m2, Urea mg/dl, Creatinine mg/dl and Alb:creatinine mg/g ) among DMT2 and without nephropathy (Control) , DMT2 with micro-albumin and DMT2 with macro-albumin show significant at baseline. From this study, it can conclude that: the measurement of serum FGF23 was of clinical value in assessment of renal damage that associated with DMT2 patients between the baseline time and after 6 months.
Full article
International Medical Journal
Journal ID : IMJ-19-06-2020-517
Total View : 301
Title : are closed reduction and percutaneous pinning sufficient in non-pathologic fractures in oncology patients?
Abstract : The incidence of hip fractures in patients with a history of cancer is expected to increase, whether the fracture is pathologic or not. This study sought to answer two decision points: (1) What is the appropriate imaging modality to determine if the fracture is pathologic? (2) Is osteosynthesis (OS) an appropriate technique in the management of femoral neck fractures in patients with a history of cancer? We did a retrospective review of patients presenting with femoral neck fractures that underwent OS or hemiarthroplasty (HA) at a single oncologic referral center. 127 patients were identified, 109 underwent HA and 18 underwent OS. Comparison of the imaging to the histologic analysis was performed to determine the accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the various imaging modalities. Analysis of radiographic imaging demonstrated the addition of advanced imaging improved the accuracy, sensitivity, specificity, PPV, and NPV compared to radiographs alone. Both HA and OS offered durable reconstructive options. Radiographs without advanced imaging for comparison are incorrect 26% of the time; advanced imaging improves the accuracy. Osteosynthesis is a durable reconstructive option in patients with a history of cancer without an underlying pathologic fracture.
Full article
International Medical Journal
Journal ID : IMJ-19-06-2020-516
Total View : 330
Title : Gram stain microscopy in septic arthritis
Abstract : Septic arthritis is a serious condition that can lead to rapid destruction of joint if it is not rapidly diagnosed and treated appropriately. The reported annual incidence is 10 in 100 000 although this increases to 70 in 100 000 in those with risk factors for developing septic arthritis mainly rheumatoid arthritis and immune-compromised patients. The aim of this study is to examine the sensitivity and specificity, and thus the clinical usefulness, of gram stain results. Single centre, retrospective case series. All joint aspirates over a three-year period from May 2015 to April 2018 were reviewed. The gram stain and final culture results noted. 830 samples were included from both native and replaced joints. Native joints accounted for a total of 701 cases (84%) of the aspirates, whilst those obtained from prosthetic joints 129 (16%). In 74 (9%) cases there was a discrepancy between the gram stain and culture results. The sensitivity of the gram stain in this case series is 22% and the specificity of the test is 99.6%. The clinician should have a low threshold for overlooking a negative gram stain result and place greater emphases on the clinical findings in conjunction with biochemical markers.
Full article
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