: The mortality rate due to cardiovascular disease in Kazakhstan is two times higher than in European countries. Coronary artery bypass grafting (CABG) is developed in Kazakhstan very quickly for many years. But there is no information about outcomes of CABG. The objective of investigation was to analyze the short-term outcomes after CABG in Kazakhstan during 2012-2018 years. This registry-based historical cohort study obtained data on all patients who underwent CABG in East Kazakhstan and Pavlodar regions of Kazakhstan between 2012 and 2018. Data are presented as the means ± standard deviation or as frequencies and percentage. The incidence rates were calculated as the number of cases per 100000 person-years of follow-up and 95% CI. Factors associated with survival were studied using Kaplan–Meier curves. A total of 4337 subjects were underwent CABG. Of these, 3198 were male, 1139 were female. The mean time to CABG was 14,96 days (SD=6,48). A total of 74 patients (1,7%) died after the surgery during in-hospital period. The mean follow-up time was significantly higher in women than in men (16,7 vs. 7,6 days, log rank p = 0.012). The mean follow-up time for patient who died in-hospital period was 10,4 (95%CI:7,6-13,3) days. Kaplan-Meier analysis of freedom from mortality revealed no significant difference between diseases (χ2=6,259, df=5, p=0,282). In-hospital mortality rate was higher in women than in men. Mortality rate was higher in patients who were admitted by emergency service. In-hospital follow-up time was significantly lower in men than in women. Freedom from mortality revealed no significant difference between diseases..