International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Lizi Jiaohuan Yu Xifu/Ion Exchange and Adsorption Fa yi xue za zhi

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-06-02-2020-213
Total View : 357
Title : Serum Adiponectin as an Early Biomarker of Systemic Lupus Erythematosus activity and lupus nephritis
Abstract : Systemic lupus erythematosus (SLE) is a chronic multi-system inflammatory connective tissue disorder, affecting kidneys in about 50% of patients. The laboratory tools used to determine kidney affection are modest and relatively inaccurate in their ability to detect SLE activity and lupus nephritis flare. Therefore, new biomarkers for proper detection of SLE activity and lupus renal disease have to be searched. To investigate serum adiponectin as a marker of SLE activity and lupus nephritis. 90 participants were involved and classified into 4 main groups; group I included 36 healthy volunteers as control group, group II included 18 patients with active SLE with lupus nephritis, group III included 18 patients with active SLE without lupus nephritis and group IV included 18 patients with inactive SLE. All participants were submitted to; urine analysis, complete blood count, fasting blood glucose, serum creatinine, liver function tests, serum complement 3 and 4, antinuclear antibody, anti-double stranded DNA level and serum adiponectin levels assays. Serum adiponectin levels were significantly higher in lupus nephritis group than in the other two SLE groups and controls. Adiponectin at a level >2.9μg/mL had a greater sensitivity 92.5% and specificity 98.3% for identifying SLE activity than both C 3 at a level < 44.4mg/dl with sensitivity 73.4% and specificity 75.6% and C4 at a level < 10.4mg/dl with sensitivity 65.2% and specificity 68.4%. Serum adiponectin could be used as an early marker for identifying SLE activity and lupus nephritis.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-212
Total View : 148
Title : Health Communication to Support Policy Advocacy of Non-Smoking Area (KTR) in the Special Region of Yogyakarta, Indonesia
Abstract : As social beings, in every activity communication activities are important things that must be done. As social beings, communication is an essential issue to do in each of their activities. One of the most important communications in human life is health communication. One of the most significant communications in human life is health communication. The purpose of health communication is as a means of delivering information or messages about health to the public. The purpose of health communication is as a way of delivering information or messages regarding health to the community. This study uses qualitative case study methods using primary and secondary data. This study employed a qualitative case study method with primary and secondary data. Primary data obtained through in-depth interviews (in-depth Primary data were obtained through in-depth interviews, interviews). Whereas secondary data is sourced from document review. while secondary data were taken from document reviews. The results of the study showed that health communication carried out by the Government of the Special Region of Yogyakarta in supporting the advocacy of No-Smoking Areas (KTR) policies through advocacy namely through the socialization of KTR policies, social support through collaboration with all elements of society and community empowerment through health education on the dangers of smoking to health to all elements of society in the Special Region of Yogyakarta. The results of the research revealed that the Special Region of Yogyakarta (DIY) carried out health communication in an effort to support advocacy for the Non-Smoking Area (KTR) through three ways: advocacy run by socializing KTR policies, social support performed through cooperation with all elements of society, and community empowerment implemented through health education regarding the dangers of smoking to health for all aspects of society in the area.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-211
Total View : 149
Title : An improved preeclampsia in vitro model using induction of preeclampsia serum in isolated trophoblast cells: a simple cell modelling protocol
Abstract : Placenta is the main factor in the pathogenesis theory for the mechanism of preeclampsia. Development of laboratory modality related preeclampsia is needed in therapy and prevention improvement. The aim of this study is to investigate optimization of the isolation protocol of primary cells of trophoblast and development of an in vitro model of preeclampsia by measuring the level of sFLT-1 and PIGF. This is an in vitro laboratory experimental study. Placenta tissue was obtained from term pregnancy with caesarean delivery. Trophoblast cells was isolated from the placenta in several steps and identified by Cytokeratin 7 (CK-7) expression using immunocytochemical method. Subsequently, cells were inducted with serum preeclampsia. Both sFLT-1 and PIGF level were measured with ELISA. Expressed CK-7 in the cytoplasm confirmed the cells were trophoblast cells. After induction, sFLT-1 increased and PIGF decreased compared with control. Trophoblast cells express CK-7 protein in their cytoplasm. Isolated trophoblast cells stained brown in the cytoplasm confirmed that these cells expressing CK-7 protein. Increased expression of sFlt-1 level in cells induced with preeclampsia serum corresponds with other research that overexpression of sFlt-1 causes clinical manifestation that is similar with hypertension in mice. Meanwhile, sFlt-1 is capable to break PIGF causing a decrease of it. Our result shown in line that PIGF level in cells induced with preeclampsia serum decreased compared with control. This protocol shown to be applicable in isolation of trophoblast cells in placenta and can be used as a basis to develop in vitro model of preeclampsia.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-210
Total View : 198
Title : A rare case of temporal bone cancer : ‘Doctor please keep my ear’
Abstract : A 65-year-old Chinese lady presented to us with a 2-month history of progressive swelling in her right ear. It was a painless swelling associated with itchiness with occasional mucoid discharge. The initial diagnosis was right aural polyp which later biopsy was taken and histopathological examination revealed moderately differentiated squamous cell carcinoma of the right external ear canal. HRCT temporal bone was reported as lobulated soft tissue mass at the right external ear canal with preauricular nodes and pressure erosion of the bony EAC. The patient underwent radical surgery followed by a referral to the oncology team for further management.
Full article
International Medical Journal
Journal ID : IMJ-06-02-2020-209
Total View : 195
Title : Incessant Atrial Tachycardia Induced Hypoxic Spell in Tetralogy of Fallot : A Case Report
Abstract : Tetralogy of Fallot (TOF) remains the most common complex cyanotic congenital heart defect. One of the main adult congenital heart disease (ACHD) concern is the late risk of arrhythmias. ACHD with cyanosis prone to induced Atrial Tachycardia (AT). We present a rare case of long-term adult survivor with uncorrected TOF who developed incessant AT induced hypoxic spell. A 34 years old women with uncorrected TOF was admitted to emergency department with chief complaint of palpitation. The electrocardiography showed atrial tachycardia 2:1. The patient refractory to many pharmacological treatments. Patient were given amiodarone, diltiazem and underwent electrical cardioversion. The catheter ablation was planned but the patient died due to hypoxic spell. Adults with cyanosis congenital heart disease has risk of AT, which patients with cyanosis have prevalence 31% vs 7.9% compared with noncyanosis. Most atrial tachycardias in patients with CHD involved a macroreentrant circuit within abnormal atrial muscle. Treatment options for AT with haemodynamically stable include vagal manoeuvre, adenosine and AV nodal-blocking agents such as ß-blocker or calcium channel blockers and synchronized cardioversion for haemodynamically instability. Catheter ablation is the treatment of choice for incessant AT. In this case, patient refractory to treatments and became incessant AT. Hypoxic spells can be induced by an atrial tachycardia. In TOF patient, with its basic arterial desaturation, diminished cerebral flow, lowered aortic and ventricular pressures, probably additional right to left shunt shunting of desaturated blood at ventricular level with rise in pulmonary vascular resistance, are superimposed during arrhythmia event. This condition maybe explained why the patient had an episode of desaturation. Arrhythmias in TOF were common. Cyanosis become risk factor for leading into arrhythmias and arrhythmias also induced cyanosis, creating a vicious circle. Acute therapy and catheter ablation were remaining golden therapy for termination of arrythmias.
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