International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley Shenyang Jianzhu Daxue Xuebao (Ziran Kexue Ban)/Journal of Shenyang Jianzhu University (Natural Science) General Medicine (ISSN:1311-1817) Chinese Journal of Evidence-Based Medicine Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation Lizi Jiaohuan Yu Xifu/Ion Exchange and Adsorption

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-10-01-2020-136
Total View : 495
Title : Association of anemia factors in kidney transplant recipient patients
Abstract : PTA has multifactorial etiology involving transplant failure, infections, co-morbidity, inflammation, ACE inhibitors/ ARBs, and immunosuppressive treatment. Anemia complicates chronic kidney disease and has been associated with increased mortality in dialysis patients. Anemia is corrected after renal transplantation, yet PTA is noted in 20% to 40% cases. This study was carried out to determine the association of anemia factors in kidney transplant recipients with and without post-transplantation anemia. After informed consent, demographic information of all the study subjects (including name, age, and gender) was recorded. The patient’s hemoglobin level was checked and they were labeled as anemic or non-anemic. In all anemic and non-anemic patients, study parameters were applied to rule out the cause of anemia. All the information was collected on a specially designed proforma. The following study parameters were measured using the standard lab procedures and manufacturer’s instructions. Using logistic regression, we found that in these patients serum B12 deficiency, low serum folate, and low serum iron were significant factors of anemia with a significant Odds ratio (i.e. OR>1) i.e. 5.913, 60.945 and 51.825 respectively. Medical complications are common after renal transplant especially in the early postoperative period. The only way forward is early recognition and aggressive treatment, as delays can cost losses in the form of kidney function, life, and higher health care cost.
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International Medical Journal
Journal ID : IMJ-10-01-2020-135
Total View : 441
Title : The Effectiveness of Patient Acuity Tool on Nursing and Patients Outcomes: A Literature Review
Abstract : This integrative literature review aimed to understand the meaning of patients’ acuity, patient acuity tool, and to investigate the effectiveness of applying patients’ acuity tool on nursing and patients’ outcomes. A search protocol was implemented using five electronic databases from January 2000 to December 2016. Thirty-nine articles were included in this paper. The findings of this integrative review showed that patient acuity tool serves as a document tool and the managers’ voice for important staffing decisions as recruitment, assignment distribution and employing new staff. The tool can assist nursing staff, and it is very important for the patients’ outcomes like the quality of care and patient safety. The patient acuity tool is a major asset for nursing management, staff, and most important for the patient. Nursing assignment, nurse s’ satisfaction, nursing workload acuity, patient acuity tools, patient classification systems, and patients’ outcomes.
Full article
International Medical Journal
Journal ID : IMJ-10-01-2020-134
Total View : 489
Title : Phytochemical Analysis and Anticancer Evaluation of Iraqi Herb Chenopodium Murale Extracted by Microwave-assisted Extraction
Abstract : Chenopodium murale is a medicinal herb with biological functions that has been studied with common extraction methods. However, studies on Iraqi C. murale (ICM) have not yet been reported. Microwave-assisted extraction (MAE) was used as a green extraction method for the first time with C. murale. The phytochemical components were profiled by GC-MS, which showed about 11 compounds. The highest peak occurred for compound 6 (phytol, acetate), followed by compounds 9 and 10, which belong to the same compound (hepatocosane). The ethanol extract displayed antioxidant action with IC50 = 102.3 µg/ml, which was compared to vitamin C as a positive control (IC50= 79.69 µg/ml). We tested the toxicity of ICM against two types of cancer cell lines, breast cancer (MCF-7) and liver cancer (HACM), for which the IC50 values were estimated as 1504 and 1267 µg/ml, respectively. Late apoptosis values were 73.4 and 58.5 for MCF-7 and HCAM, respectively, and cell cycle arrest occurred in the G1 phase for HCAM and the G2 phase for MCF-7. The results were compared with control cells. In vitro, normal kidney cells showed limited toxicity from the extract, which was compared with highly toxic doxorubicin as a positive control. The results suggest that the MAE method for ICM produced selective bioactive compounds, which may behave as potential natural anti-breast and anti-liver cancer agents. The results could help in the development of future investigations with regular doses to prevent liver and breast cancer.
Full article
International Medical Journal
Journal ID : IMJ-10-01-2020-133
Total View : 377
Title : OPTIMIZATION OF NANOEMULSION GEL FORMULATION OF MANGROVE LEAF EXTRACT (Acanthus Illicifolius)
Abstract : Mangrove leaf is one of the plants that grow in the waters of the island of Java that has potential as a medical plant. There have been many people living around the cultivation of mangrove leaves who have used mangrove leaves as a medicine that is to treat pain. One type of mangrove species that has potential as a medicinal plant is the Acanthus illicifolius mangrove. However, the use of mangrove leaves for treatment has not yet found as an easy and practical dosage form. People only use it by pounding it and affixing it to the sick part. This study aims to determine the nanoemulsion gel formulation of mangrove leaf extracts with a comparison of Na CMC concentrations so that easily used by the public. This research is an experimental study comparing the concentration of the gelling agent as the basis for making nanoemulsion gels. This study used three formulations of nanoemulsion gel preparations namely Na CMC 3%, Na CMC 4%, and Na CMC 5%. The results of this study are seen from the organoleptic test that nanoemulsion gel using 3% Na CMC produced a too runny preparation and 5% Na CMC preparations that were produced were too thick so that resulting preparation could not be tested for the physical properties of the preparations. For preparations that use 4%, Na CMC produce is good manufacturing product of nanoemulsion gel, so that it’s proceeded to the stages of testing the physical properties of nanoemulsion gel preparations.
Full article
International Medical Journal
Journal ID : IMJ-08-01-2020-130
Total View : 488
Title : Relationship between TOP2A mRNA Expression with Neoadjuvant Chemotherapeutic Response in Breast Cancer
Abstract : Anthracycline is commonly used in neoadjuvant chemotherapy for breast cancer, although not all patients benefit from the therapy. Studies suggest that expression of TOP2A associated with Anthracycline sensitivity. Purpose: To know the relationship between the profile of baseline TOP2A mRNA expression and chemotherapy response in locally advanced breast cancer. An observational study, thirty breast cancer tissue samples pre-chemotherapy treated using cyclophosphamide-doxorubicin-5fluorouracyl regiment. Detection of TOP2A mRNA expression using qRT-PCR techniques. Clinical response to neoadjuvant chemotherapy based on RECIST criteria. The mean value of TOP2A mRNA expression in breast cancer patient’s prechemotherapy was 9.753±2.755, range 4.470–13.810. The mean value of TOP2A mRNA expression in breast cancer patients which responsive to chemotherapy was 10.601±2.208. The mean value of TOP2A mRNA expression in breast cancer patients, which nonresponsive to chemotherapy, was 6.969±2.648. Mean difference was 3.632, significant with p-value =0.001(p<0.05). There is a positive correlation between TOP2A mRNA expression with the clinical response with a value of r =0.475; this correlation was significant with p-value=0.004 (p<0.05). This study found a correlation between the profile of baseline TOP2A mRNA expression with clinical response to neoadjuvant chemotherapy in breast cancer.
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