International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal.

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-17-03-2020-352
Total View : 131

Abstract : Population are getting older in the statistics by the WHO. Today for the first time in history most people can expect to live into their 60s and beyond. One of the main concerns of medical professionals and researchers is definitely healthy aging. The healthy aging is a key to longevity. The people of the Asia have been used various plant, aninal and mineral-originated medicines for rejuvenating and improving strength. There are about 300 formulas based on 99 different materials derived from plants, animals and minerals. The five roots have been used as rejuvenating remedies in traditional medicine. To examine the effects of aqueous and ethanol extracts of the five roots on cisplatin-induced testicular injury in rats. Aqueous (994 mg/kg) and 70% ethanol (874.4 mg/kg) extracts were given orally for 10 consecutive days. Cisplatin was administered intraperitoneally (7.5mg/kg) on the last day of the five roots treatment. Dehydroepiandrosterone (DHEA), Cinaspol were used as comparisons. Blood levels of testosterone were determined by enzyme-linked immunosorbent assay. Sperm motility and concentration were determined by Ds microscope and NIS-Elements. Caspase-3 and ВcL2 gene expressions were examined by Q-PCR. Testicular weights, sperm motility, sperm concentration and plasma levels of testosterone were significantly decreased in rats administered cisplatin (p<0.05) and these were significantly increased by aqueous and ethanol extracts of the five roots, DHEA, Cinaspol compared to untreated model. Aqueous and ethanol extracts of the five roots restore testicular functions by increasing blood levels of testosterone, sperm motility, sperm concentration, reducing testicular necrosis in rats administered cisplatin.
Full article
International Medical Journal
Journal ID : IMJ-17-03-2020-350
Total View : 117

Abstract : Hemodialysis therapy will change the rhythm of a person's life for a long time. It can cause depression which is characterized by changes in behavior such as rejection, anger, fear, feelings of helplessness, hopelessness, anxiety and even suicide. If depression is not handled immediately, it will worsen the quality of life of hemodialysis patients. The purpose of this study was to examine the correlation and differences between the level of depression and the quality of life of hemodialysis patients. The study employed the descriptive comparation and correlation with cross sectional approach. The study was conducted on hemodialysis patients at Public Regional Hospital of Wates Kulon Progo, Yogyakarta, Indonesia. The sampling technique used total sampling. The number of samples in this study were 64 respondents. The research instruments were the Beck’s Depression Inventory (BDI) and QoL-SF36 questionnaire. The analysis test used the Mann Whitney difference test and the contingency coefficient correlation test. The results of the study showed that the majority of hemodialysis patients were 45-54 years (32.8%), male sex (57.8%), with education background of elementary & junior high school (51.6%), married (90.6%), unemployment (28.1%), not depressed (45.3%), and with a moderate quality of life (67.2%). There was a significant difference (p = 0.023), and there was a correlation between depression and quality of life (0.008). It is expected that nurses work together with patients' families to increase patient’s acceptance to the disease, as well as measure depression levels and quality of life regularly.
Full article
International Medical Journal
Journal ID : IMJ-17-03-2020-349
Total View : 154

Abstract : The oral intake of alpha linolenic acid (ALA) has been reported to be effective in preventing vascular disease and improving blood fat status. However, the effects of ALA-rich perilla oil consumption on individuals’ physiological indicators have not been appropriately investigated. This study therefore investigates the effects of the oral intake of perilla oil on physiological indicators. Thirty-eight participants were recruited from Fukutomi-cho, Higashi-hiroshima City, Hiroshima Prefecture, Japan. The participants each took 5 ml of perilla oil daily for eight months. We calculated the mean values of the physiological index before and after the intake period and applied a paired-sample t-test. The results show that there was no change in body weight, body fat, blood lipid, or blood pressure. However, in addition to changes in the indicators of arteriosclerosis and anemia associated with aging, we observed a significant decrease—approximately 20%—in two kinds of blood oxidation markers and hormones related to bone metabolism. Participants’ scores on the self-evaluated depression scale also decreased significantly. These results suggest that daily intake of perilla oil may be useful in alleviating the effects of aging and depression.
Full article
International Medical Journal
Journal ID : IMJ-15-03-2020-347
Total View : 162

Abstract : Community-acquired pneumonia (CAP) is a common disease with a high hospitalization and mortality rate. The choice of appropriate empirical antibiotic treatment is still a matter of debate. The aim of the study was to analyze the prevalence of different antibiotic regimens and their impact on clinical outcome in hospitalized patients with CAP and to assess the impact of the corticosteroids on the in-hospital mortality. 1292 consecutive patients hospitalized at the Clinic of Pneumonology and Phthisiatrics of UMHAT “Saint Marina” – Varna were retrospectively studied for the period 2012 to 2015. The in-hospital mortality was 11.5%. The severity of pneumonia was assessed by CURB-65. The most commonly used therapeutic regimens were: beta-lactam monotherapy (34%), beta-lactam/fluoroquinolone combination (33.1%), and beta-lactam/macrolide combination (23.5%). The combination of beta-lactam/macrolide was associated with the lowest in-hospital mortality rate - 4.8%; OR 0.45 (95% CI 0.25-0.8), p <0.001, lowest rate of treatment failure (15.4%), p<0.001 and shortest hospital stay (7.76 ± 2.82 days). In severe CAP (CURB≥3), this combination showed  significantly lower in-hospital mortality of 33.3%, whereas the mortality on beta-lactam/fluoroquinolone combination  was 50% (p <0.001). The treatment failure was significantly associated with increased in-hospital mortality (16.7% vs. 6.8%, OR 2.76 (95% CI 1.83-4.16), p <0.001. There was no significant difference in mortality rate between patients treated with or without corticosteroids (7.9% vs 8.9%, p> 0.05). The combination of beta-lactam/macrolide was associated with better clinical outcomes. The choice of appropriate  initial antibiotic treatment is crucial for the prognosis.
Full article
International Medical Journal
Journal ID : IMJ-15-03-2020-346
Total View : 152

Abstract : Ultrasound-guided supraclavicular brachial plexus block reduces the probability of major complications occurrence. Adjuvants are added to local anesthetics to improve various block characteristics. Clinical and preclinical data demonstrate the analgesic actions of adenosine. The present study aims to compare the analgesic efficacy and safety of ultrasound guided continuous supraclavicular brachial plexus block using levobupivacaine alone and that of levobupivacaine combined with adenosine for anesthesia and pain control in upper limb cancer surgery. Outcome parameters included success rate, time of onset of the sensory block, motor block, visual analogue scale (VAS) for pain, at 30 min, 2 h, 12 h, 24 h, 36 h, and 48 h postoperatively, time to first rescue analgesia and analgesia related complications. The study included 120 adult ASA I-II patients scheduled for different upper limb cancer surgeries. A bolus dose is 40 ml of 0.25% of levobupivacaine alone in LB group or 40 ml of 0.25% levobupivacaine + 12 mg adenosine in LBA group. We noted significantly shorter time to sensory block in the LBA group. However, no significantly differences were noted between the studied groups regarding motor block score. Also, there were significantly lower VAS values in LBA group throughout the study assessment intervals. Moreover, there was significantly shorter time to rescue anesthesia in LB group. Both groups had equal success rates (98.3 %) with no side effects. In conclusion, adding adenosine to levobupivacaine during ultrasound-guided supraclavicular brachial plexus block has many advantages but it doesn’t affect the analgesic success rate.
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