Abstract : Ventral hernias are one of the most common challenging problems which the general surgeons confront. The rate of incidence of ventral incisional hernia in the long term after laparotomy has been reported to be 20-25%. Primary suture repair remains one of the oldest techniques. The use of sutures to fix these meshes is associated with complications like infections, seroma, fistulas and chronic pain. Self-gripping mesh has shown promising results in several different kinds of abdominal wall hernias. The aim of our study was to compare outcomes of self-gripping mesh with sutured polypropylene mesh and highlight its promising results. Our study was a comparative interventional study, carried out at SRM medical college hospital between April 2021 to October 2021, in which 80 patients undergoing open ventral hernia repair were selected as per satisfaction of inclusion criteria and divided into two groups: Conventional sutured mesh as Control group and Self- gripping suture-less mesh as Study group. This study was conducted after obtaining the institute human ethics committee approval. The intra- operative time, post-operative pain, post- operative infection and duration of hospital stay were recorded for all these patients and analysed. Based on the study, it was found out that the use of self-gripping mesh was found have less intra -operative time, less post- operative pain and infection and those patients had short hospital stay compared to sutured mesh. Thus self- gripping mesh is worthier as there is no sutures. It is time saving, surgeon friendly and improves patient’s quality of life.