Abstract : The current Corona virus disease pandemic (COVOD 19) has had a wide-ranging social and economic impact throughout the world. The present COVID-19 epidemic has prompted scientists throughout the world to look for remedies in terms of SARS-CoV-2 treatments and vaccines. Since the genomic sequence of SARS-CoV-2 was published on January 11th, 2020, an unprecedented effort to create a vaccine against the disease has been underway. On January 5th, 2021, the World Health Organization (WHO) reported that there are 63 candidate vaccines in human clinical trials and more than 172 candidates in preclinical development throughout the world. In this review, around 60 articles and newsletters were reviewed from the internet source and databases like PubMed, Scopus, Google Scholar, Embase using the key words novel corona virus, SARS CoV 2 structure, vaccines, treatment, recent advances, clinical trials. A simple concise review is written based on around 40 articles.