Vol - 25, Issue - 6
About the Journal
[This article belongs to Volume - 25, Issue - 6]
International Medical Journal
Journal ID : IMJ-19-05-2020-473
Total View : 246

Abstract : The aim of this research were to determine the anti-inflammatory activity infusa extract of katola (Arcangelisia flava (L.). Merr.) on cyclooxygenase-2 enzyme expression in Wistar rats induced Complete Freund,s Adjuvant (CFA). The examination was using immunohistochemical methods. Immunohistochemical preparations were made to treat the experimental animals as inflamed with Complete Freund,s Adjuvant (CFA) induction. The conclusion was the infusa of katola stem bark (A.flava (L.) Merr.), which consisted of Berberine HCl 5.69±0.18 (rerata±SD) at the dose 450 mg/kg BW significantly decreased the expression of COX-2 different from negative control, the level at significantly by 95%, p<0.05

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