Vol - 25, Issue - 3
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[This article belongs to Volume - 25, Issue - 3]
International Medical Journal
Journal ID : IMJ-04-03-2020-317
Total View : 124

Abstract : Erythrocyte enzyme glucose-6-phosphate dehydrogenase deficiency may result in hemolytic anemia. It is a typical x-linked pattern. Hemolysis is generally associated with Heinz bodies formation in mature red cells. A descriptive cross-sectional study. A total of 117 neonates was enrolled in the study. Complete blood count, Retic count, Retic stain for Heinz’ bodies and other tests were performed for all of the neonates. Screening for G6PD enzyme showed that 45(38.5٪) of cases were G6PD deficient. Mean G6PD level decrease with increasing serum bilirubin level (P=0.0001). Patients with positive Heinz body had a low mean enzyme level 4.88±1.23 with a range of (2-8.9). while participants with negative reticulocyte stains for the Heinz body had a high serum level of G6PD (12.72±1.79). We conclude from this study that, there is a significant difference in the mean bilirubin level between G6PD deficient neonates and other icteric neonates

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