Abstract : Cancer pain is recognized as a common cause of mental and physical suffering for patients and it affects all aspects of their well-being. In Jordan, there is a high incidence of reported cancer pain among oncology patients, but lack of evidence about patients' knowledge and experiences of cancer pain. The purpose of this study was to explore Jordanian oncology patients' knowledge and experiences toward cancer pain. A cross-sectional descriptive design was implemented. Participants were recruited from four large hospitals in Jordan through convenience sampling. Participants’ knowledge and experiences of cancer pain were measured by the Patient Pain Questionnaire (PPQ). A sample of 254 adult patients participated in the study. Most of the participants were married (78.7%), had positive family history of cancer (59.1%), and were Muslims (96.5%). The mean score for the knowledge subscale was 52.6 (SD=9.4) out of 90. The mean score for the experiences was 36.8 (SD=8.5) out of 70. There was a negative association between the mean of the knowledge subscale scores and patients' age. Significant differences in cancer pain knowledge and experiences were found according to level of education and patients’ primary care giver. This study concludes that oncology patients in Jordan have lack of knowledge and worse experience of cancer pain. The study findings imply a need for immediate actions that improve cancer pain management in Jordan. Additionally, raising awareness about pain and its negative impact on quality of life is a necessity for patients and their family.