Abstract : <p>When a cancer patient tests positive for Covid-19 infection, the patient&#39;s oncologist has to decide on a further treatment with careful consideration of factors such as patient&rsquo;s immune status, risk benefit ratio, safety of healthcare professionals and many other factors depending on the tumor&rsquo;s unique biology. Owing to the high infectivity and rapidly spreading nature of the covid-19 virus, there is little data available in order to help us arrive at the decision on the right course of treatment for cancer patients who test positive for covid-19. Special concerns are with cancer patients who are found to be persistent virus shredders and remain virus positive for more than 2 months after symptom resolution. Amidst the pandemic and all the troubles, it brings to the cancer management, organisations such as The American Society of Clinical Oncology (ASCO), American Society for Radiation Oncology (ASTRO), The United States Centers for Disease Control and Prevention (CDC) and many others have published guidelines in treating cancer patients to maximise benefits and minimise the adverse outcomes of the virus. In this mini-review, we have given a comprehensive overview on appropriate anti-cancer treatment courses if found covid-19 positive. A brief discussion on the management of cancer patients if they turned out to be persistent virus shedders.</p>