Abstract : Oral and oropharyngeal malignancies is a recognized major public health concern all over the world. They are amongst the commonest malignancy in India and accounts for up to 20% cancer burden in India. It is a prospective study done over 2 years period in population with history exposed for tobacco and alcohol addiction, at Dr.D.Y.Patil Medical College, Pimpri a tertiary care hospital to study the incidence of head and neck malignancy considering the age, type of malignancy, site, presentation, its histopathological grade and patient compliance for treatment (surgery/radiotherapy/chemotherapy), post-operative complications, its management. Total of 12 cases of oral and oropharyngeal malignancies in patients were observed in ENT OPD in tertiary hospital over a period of 2 years. All the diagnosed cases were confirmed by biopsy/histopathology, out of which 8 patients were operable. 8 patients underwent surgery. Most of the patients are managed by chemotherapy and radiotherapy. Carcinoma tongue and carcinoma buccal mucosa accounted for most of the cases. Mean age of patients which accounted for most of the cases belonged to 41-50 years old with carcinoma tongue being the most common and moderately differentiated carcinoma being the most common type of differentiation. Most commonly men are affected in large number than women. In conclusion tobacco consumption was found to be a stronger risk factor for head and neck cancer than alcohol consumption. It is also found from our study that most commonly male population are affected than female population. The most common site of carcinoma is buccal mucosa.