Vol - 28, Issue - 11
About the Journal
[This article belongs to Volume - 28, Issue - 11]
International Medical Journal
Journal ID : IMJ-18-12-2021-1101
Total View : 500

Abstract : Hyperpigmentation of the skin represents one of the major dermatological concerns for populations with pigmented skin phototypes, with a high prevalence in the Indian population. Our study was conducted to correlate histopathological and clinical findings of various hyperpigmented skin lesions in a tertiary care centre. A prospective study over a period of 2 years was conducted and included 78 cases. Biopsies of various hyperpigmented skin lesions coming to the pathology department were analysed. Both acute and chronic hyperpigmented skin lesions of all age groups and of both sexes were included. Those cases without any history of hyperpigmentation, inadequate biopsy material and those without a proper clinical history were excluded. Skin biopsy samples were processed, slides were stained by routine H&E stain and histopathological analysis was carried out. Special stains were applied wherever required (Ziehl-Nelson, periodic acid Schiff, Congo red etc). Hyperpigmented lesions were predominant in age group of 21-40 years, males, least occurrence was seen above age of 60yrs. The most common site being upper limbs and most common type of lesions were plaques. Most common clinical and histopathological diagnosis was lichen planus. Clinicopathological corelation was found to be 80.7%. Hyperpigmented lesions are a common occurrence but with a widely different aetiology. Commonest diagnosis was lichen planus both clinically and histopathologically. Histopathological study remains the gold standard for the diagnosis of hyperpigmented lesions and should be sought for to obtain an early diagnosis.

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