Vol - 29, Issue - 05
About the Journal
[This article belongs to Volume - 29, Issue - 05]
International Medical Journal
Journal ID : IMJ-04-05-2022-1419
Total View : 382

Abstract : Guided bone regeneration (GBR) is frequently used in conjunction with titanium implant placement. A key principle of GBR is the use of a membrane to prevent non-osteogenic tissues from interfering with bone regeneration. Membrane components have a variety of properties that can be modified as per the anatomic region. For experimental and clinical verification, a substantial majority of membranes have been introduced. This necessitates an update on membrane properties and biological outcomes, as well as a critical examination of the biological mechanisms dictating bone regeneration in membrane-covered defects. Experiment results indicate that modifying the physicochemical and mechanical properties of membranes may promote bone regeneration. Nonetheless, the precise role of membrane porosities in GBR membrane barrier function remains unknown. In addition, rather than being a passive barrier, novel experimental findings suggest that the membrane compartment itself plays an active role in promoting regenerative processes in the underlying defect during GBR. An important strategy in this field of research is the optimization of membrane materials by systematically addressing both the barrier and the bioactive properties.

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