Abstract : Mass in the right iliac fossa has a very high incidence rate among the cases of lump in abdomen. It’s a diagnostic and therapeutic challenge to surgeons due to the detailed anatomy of the region and varied etiology. To study the demographic profile of right iliac fossa mass. In this prospective comparative study, total 50 cases were studied for duration of 2 years. Detailed demographic data was obtained after confirming the diagnosis. Necessary management was done. Comparison of all the data with various demographic parameters was done to reach conclusion. Maximum cases were from age group of 31-40 yrs with mean age was 40.76 years and male predominance (58%). Appendicular lump (28%) was most common diagnosis among study subjects followed by ileocaecal tuberculosis (14%). Farmers and labourers were more prone to develop mass in right iliac fossa. Mass in right iliac fossa is commonly seen in males of age group 31 to 40 years with low socioeconomic status. Appendicular mass is most common pathology in RIF region although ileocaecal tuberculosis also have good incidence rate. Due to its varied presentation, high index of suspicion is absolutely necessary for diagnosis and management of right iliac fossa mass.