Abstract : Garments manufacturing industry is highly labor-intensive especially in developing countries like Pakistan. Most of the times the labor has to work in adverse conditions. Despite of the developments in workshop practices and technology, garment industry is among the most labor-intensive industries. The working generally consists of long hours with one lunch break in the middle of the day. These workers are rarely provided with appropriate workstations and weak social infrastructure adds to the risk of discomfort and illness. But such risks are rarely investigated at workplace. The objective of this research is to determine the Ergonomics risk factors for workers in clothing manufacturing and its association with musculoskeletal problems in Raiwind city Lahore. Analytical cross sectional was conducted. 335 participants from clothing industry were included. Rapid Entire Body Assessment was used for risk factors associated. Nordic Musculoskeletal Questionnaire was be used to assess musculoskeletal problems. There is significant difference of NORDIC and REBA score between types of equipment use with participates using manual equipment having higher NORDIC and REBA score. There is strong positive correlation between REBA risk measurement and NORDIC musculoskeletal disorders. This study concluded that there is strong positive correlation between REBA risk measurement and NORDIC musculoskeletal disorders. Increasing ergonomic risk increases musculoskeletal disorders. It also concluded that Female workers have higher ergonomic risk and musculoskeletal disorders, workers using equipment have higher ergonomic risk and musculoskeletal disorders, workers having more than 5 years of xiv experience have higher ergonomic risk and musculoskeletal disorders, workers in seating working position have higher ergonomic risk and musculoskeletal disorders, workers using manual equipment have higher ergonomic risk and musculoskeletal disorders.