Vol - 25, Issue - 4
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[This article belongs to Volume - 25, Issue - 4]
International Medical Journal
Journal ID : IMJ-11-04-2020-409
Total View : 141

Abstract : <p>Context: Drug delivery through enteral feeding tubes (EFT) is complex and prone to errors. Aims: To identify errors of oral medication preparation and administration in adult patients with nasogastric tube (NGT) and their associated factors on blockage of the tube. Settings: A cross-sectional study was performed in March–June 2018 in six units at a tertiary level hospital in Yogyakarta, Indonesia. Methods: Seventy-nine patients with 106 oral therapy preparations following administrations via EFT, which were carried out by nurses, nursing assistants, and caregivers, were prospectively observed. The evaluation of errors used a standard checklist. Blockage of feeding tube was observed in the NGT hose. Data of patient characteristics were analyzed by descriptive analysis. Data of the association between variables were examined using bivariate analysis by chi-square test, whereas multivariate logistic regression was used to identify possible factors associated with feeding tube blockage. Results: The patients were mostly female (51.9%), middle-aged with age range of 41–64 years (49.4%) and with NGT bore size of 16 French (97.5%). Non-dilution with water of commercially available liquid forms of drugs (71.43%) was the most common preparation deviation from the guidelines. The most frequent improper administration involved not flushing the NGT with water between drug administrations (91.51%). An association was observed between occluded NGT and the incidence of preparation error, which involved crushed tablets or capsules, with p value < 0.05. Conclusions: Successful drug delivery through EFT requires the consideration of physicochemical drug and dosage form properties</p>

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