Abstract : This study focussed on evaluation of the addition of titanium dioxide (TiO2) nanoparticlesto conventional glass-ionomer (GC Universal Restorative Cement 2) on Vickers microhardness and shearbond strength. This study was an in-vitro experimental study. This study was carried out at Pakistan Instituteof Engineering and Applied Sciences (PIEAS). It was completed in two and half months i.e from 1stJanuary,2019 till 15 March,2019. Titania nano particles were added in conventional glass-ionomer (GCUniversal Restorative Cement 2) at 3%, 5% (w/w). Unblended powder was used as control group (Group 1)while glass-ionomer containing titania nano particles at 3% (w/w) was considered as (Group 2) and glass–ionomer containing titania nano particles at 5% (w/w) was considered as (Group 3). Diamond indentor wasused to measure surface microhardness. Cylinders of all groups (9.5X1mm) were prepared. Total of 9sample cylinders were prepared. Shear bond strength was measured using universal testing machine. Humananterior teeth were used to measure shear bond strength. Blocks of all three groups (4X4X1mm) wereattached to treated enamel and dentin surfaces. Total of 18 human anterior teeth were used to measure shearbond strength, 6 teeth for each group (3 for enamel and 3 for dentin). SEM analysis of specimen of flexuralstrength test was done before and after test. One-way ANOVA analysis was conducted to compare the shearbond strength and microhardness between the three groups. Post-hoc Tukey analysis was used to compareinter-group mean differences. An arbitrary significance value of 0.05 was considered to be significant. Alldata was entered and analysed using SPSS v 23.0. Results showed significant increase in microhardness(p<0.05) and significant increase in shear bond strength (p<0.05). Conclusions: GI-containing 3% and 5%(w/w) TiO2 nanoparticles are restorative material with enhanced mechanical properties. This interestingexperimental Glass-ionomer may be used for higher stress-bearing area restorations such as Class I and II