Abstract : As social beings, in every activity communication activities are important things that must be done. As social beings, communication is an essential issue to do in each of their activities. One of the most important communications in human life is health communication. One of the most significant communications in human life is health communication. The purpose of health communication is as a means of delivering information or messages about health to the public. The purpose of health communication is as a way of delivering information or messages regarding health to the community. This study uses qualitative case study methods using primary and secondary data. This study employed a qualitative case study method with primary and secondary data. Primary data obtained through in-depth interviews (in-depth Primary data were obtained through in-depth interviews, interviews). Whereas secondary data is sourced from document review. while secondary data were taken from document reviews. The results of the study showed that health communication carried out by the Government of the Special Region of Yogyakarta in supporting the advocacy of No-Smoking Areas (KTR) policies through advocacy namely through the socialization of KTR policies, social support through collaboration with all elements of society and community empowerment through health education on the dangers of smoking to health to all elements of society in the Special Region of Yogyakarta. The results of the research revealed that the Special Region of Yogyakarta (DIY) carried out health communication in an effort to support advocacy for the Non-Smoking Area (KTR) through three ways: advocacy run by socializing KTR policies, social support performed through cooperation with all elements of society, and community empowerment implemented through health education regarding the dangers of smoking to health for all aspects of society in the area