Vol - 28, Issue - 08
About the Journal
[This article belongs to Volume - 28, Issue - 08]
International Medical Journal
Journal ID : IMJ-05-09-2021-920
Total View : 394

Abstract : The objective of the present study is to evaluate the invitro attenuation of coagulation by Dracaena sanderiana. Prothrombin time assesses coagulation factors in extrinsic pathway (factors VII) and common pathway (factors X, V prothrombin and fibrinogen), thus with the help of UNIPLASTIN reagent a protocol has been prepared to evaluate the anticoagulant activity of Dracaena sanderiana. It was observed that Dracaena sanderiana at different concentrations significantly prolonged the clotting time in a concentration dependent manner against the standard EDTA. Thus, it can be concluded that the ethanolic extract of Dracaena sanderiana possesses pharmacologically active anticoagulant component which might be helpful to for blood coagulation disorders.

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