Abstract : This study was conducted to understand the abnormalities in liver functions in children with Dengue fever and its associations with the outcome. The aim of this study was to assess liver functions SGOT (AST) & SGPT(ALT), Serum Albumin in children with Dengue fever. To study the association of liver function tests with clinical stages of dengue fever and outcome with the severity of liver enzymes. This Prospective study was conducted in Paediatric wards of NKPSIMS & LMH, Nagpur from 1st January 2019 to 31st December 2019. During the study period 124 children in the age group upto 18 yrs presenting with fever and positive serology for dengue were included in the study. Children who were diagnosed as Dengue like illness but were serologically negative and those with cirrhosis, chronic liver disease or concomitant infection with malaria, Hepatitis A, Hepatitis B, enteric fever were excluded from the study. During the one year study period 124 children were admitted as serologically positive dengue patients. Among them 80 (64.51%) were male and 44(35.46%) were female. Maximum children were in age group of > 5yrs. Patients with dengue fever without warning signs were 73(58.87%), 44(35.48%) were dengue with warning signs and 7(5.65%) were cases of severe dengue. The SGOT(AST) levels were more than 300 in 22.8% while SGPT (ALT) levels were raised in only 2.41%. Out of the 28 children with SGOT (AST) levels > 300IU/L 28.57% of children had serum albumin levels <2.5g/dl. Patients with SGOT (AST) & SGPT (ALT) levels of more than 300IU/L had hospital stay of more than 7 days. Of the total 28 patients who had SGPT(AST) levels more than 300U/L, 6 (21.42%) patients had complications in the form of ascites and pleural effusion and 2 (7.14%) patients had severe bleeding. The mortality rate in our study was 0.08%. Liver Function Tests derangements are seen in all forms of dengue fever. Higher SGOT (AST) levels as compared to SGPT (ALT) were seen in patients with severe Dengue which was also associated with prolonged hospital stay. A significant rise of liver enzymes helps in the recognition of severe forms of dengue infection.