Vol - 29, Issue - 02
About the Journal
[This article belongs to Volume - 29, Issue - 02]
International Medical Journal
Journal ID : IMJ-03-02-2022-1241
Total View : 468

Abstract : To study the prevalence of fungal neonatal sepsis in very low birth weight neonates and to study the risk factors that increase fungal neonatal sepsis. It was a single centre, prospective observational study conducted in NICU in the Department of Paediatrics at a tertiary care centre, Nagpur. All very low birth weight neonates were enrolled in the study after obtaining proper consent from parents. Out of all the VLBW neonates who had at least one blood culture positive were taken as cases. The demographic data like name, sex, age at admission, registration number, Gestational age, birth weight, number of days stay in NICU were recorded. Out of 71 newborns, 10 (14.09%) were culture positive and 61 (85.91%) were culture negative. Out of 10 culture-positive cases broad-spectrum antibiotics were given to 8 cases (80 %) while no antibiotics were given in 2 cases (20%). Ventilation was required in 3 cases (30%) and 7 cases did not require ventilation (70%). The survival rate was 8 (80%) in our study while 2 (20%) neonates succumbed. Fungal (Candida) sepsis is a predominant cause of neonatal sepsis. Very low birth weight neonates (< 1500 mg), use of broad-spectrum antibiotics, and mechanical ventilation were found to be significant risk factors as well as important predictors of mortality in fungal sepsis in neonates. The significantly higher mortality of VLBW infants with nosocomial infections as compared to those without, stresses the need for strict and regular surveillance of this problem.

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