Abstract : Heart failure can influence all aspects of patients' health despite the improvement in its treatment. Different factors might affect the quality of life for patients with heart failure. These factors might include: age, gender, ejection fraction, culture, social support, and perceived control. The purpose of this study was to check the effect of perceived control on quality of life among patients with heart failure in Jordan. A cross-sectional correlation design was used with a sample of 220 patients with a confirmed diagnosis of heart failure. Data were collected using 36-Item Short Form Survey and the Control Attitudes Scale-Revised. Data were analyzed using multiple regression. The mean age was 53.24±8.92 years with a duration of heart failure diagnosis ranged from 1-15 years. Perceived control mean was 26.90±4.42. Patients reported poor quality of life in role physical, general health, vitality domains, and physical component summary, indicating poor quality of life. In multiple regression, higher levels of (Left Ventricular Ejection Fraction and perceived control) improved physical and mental component summaries. In conclusion, Jordanian patients with heart failure reported poor quality of life and relatively high levels of perceived control which improves the quality of life. Interventions improving perceived control in those patients might enhance the quality of life, and decrease mortality and morbidity.