Abstract : The caries arrest and prevention effect of silver diamine fluoride (SDF) offers a non-invasive and reasonable treatment option in comparison to invasive restorative treatment modalities. However, the staining effect of SDF might force Parents/Guardians (P/G) to reject such treatment due to the change in child esthetic. This cross-sectional study aimed to evaluate P/G perceptions of SDF staining produced on anterior and posterior teeth of children with cooperative and uncooperative behaviours. The study model included 62 P/G attended a private pediatric dental clinic centre in Baghdad/Iraq. The P/G accompanied children aged 3-5 years with a high risk of dental caries. Two clear and easy to complete questionnaires were dispensed to the P/G and health care providers to report their responses about SDF staining effect and child cooperation respectively. SDF solution applied to carious lesions of primary teeth by health care providers. Standardised digital images before and after treatment were shown to the P/G to rate whether dark staining is an acceptable or unacceptable result. Responses were analysed using the chi-square test in SPSS software. The results showed a significant association between the P/G acceptance or unacceptance of staining and the area of treatment. Generally, P/G accepted staining on posterior teeth more than anterior teeth especially for those children with un-cooperative behaviour. In conclusion, change in esthetic is a prime concern that affects P/G perception of the treatment between anterior and posterior teeth. However, child behaviour can significantly modulate that perception