Abstract : The objective of this study was to determine phage types, biotypes and antimicrobial resistance patterns and their correlation of Salmonella enterica serotype Typhi and Salmonella enterica serotype paratyphi isolated from blood, so that appropriate strategies can be adopted in the management of enteric fever. A total of 22 S. enterica serotype Typhi isolates from 300 blood samples from BacT alert system were send for phage typing and biotyping to Lady Harding Medical College New Delhi and also tested for their antimicrobial susceptibility profile. Out of 22 strains 2 strains were not revived, so we got report of only 20 strains The commonest phage type was E1 10(50%), some strains were Deg vi (degraded Vi) strains 5(25%), and Vi negative strains 1(0.05%). UVS (Untypable vi strains) 2(10%) and two strains were Phage type 2(10%) A single phage type and biotype were prevalent among the Salmonella enterica serotype Typhi and Salmonella enterica setotype paratyphi isolates studied from Aurangabad, Maharashtra.