Abstract : The aim of this study was to determine the prevalence of musculoskeletal disorders amongst teachers in the UAE, and further extend to examine the association of musculoskeletal disorders in teachers in the UAE with a) Socio-demography, b) work, c) social, d) psychological factors and to assess predictors of musculoskeletal disorders amongst teachers. The Nordic Musculoskeletal Questionnaire (NMQ) and A validated questionnaire containing questions of predictors was distributed to teachers of four schools in Ajman and Dubai and 371 teachers responded. The most common site of pain reported was neck pain at 43.7% for 12-month history and 24.5% for 7 days, followed by lower back pain at 42.6% in the last 12 months and 24.1% in the last 7 days. Musculoskeletal pain was more prevalent among female gender, higher body mass index (BMI), more than 7 years of work, and with self-reported anxiety, depression, and high work stress. Musculoskeletal spinal pain such as neck and back pain among teachers was highly prevalent and risk factors associated were age, gender, BMI, years of work, regular exercise, hours of sleep, depression, and stress.