Abstract : Breast neoplasms show varied histopathologic presentations that pose diagnostic challenge to the reporting oncopathologists. Eight of such cases have been discussed here. A case of 56 years old women showed high grade pleomorphic features on cytology. Biopsy was negative for ER, PR, HER2, melanocytic markers, CD45, cytokeratin, CD99 & CD34. It was positive for Vimentin. A diagnosis of Undifferentiated Pleomorphic Sarcoma of breast was delivered. A very rare diagnosis of Myxoid Liposarcoma of breast was made in a 66 years old female. Invasive Breast Carcinoma-No Special Type with Medullary pattern was seen in a 60 years old female. A 55 years old lady with breast tumor showed invasive growth pattern with >90% papillary architecture. Histopathological diagnosis was that of Invasive Papillary Carcinoma of breast. A fairly rare case of Metaplastic breast carcinoma was seen in a 65 years old female. The other three rare cases were bilateral Pleomorphic Ductal Carcinoma in a 45 years old female, Invasive Breast Carcinoma with Neuroendocrine differentiation in a 50 years old lady and Secondary (Diffuse Large B Cell Lymphoma) DLBCL in Breast in a 60 years old lady. Vivid histopathological examination along with judicious use of immunohistochemical and radiological observations helped in arriving at definitive diagnosis of these unusual breast lesions.