Home
About Us
Information & Guidelines
Article Processing Charges
Open Access Policy
Terms and Conditions
Privacy Policy
User Feedback
Information For Authors
Information Editorial Board
Contact Us
FAQ
Paper Submission Guideline
Register
Login
Submit Now
Vol - 25, Issue - 5
Full-Text PDF
About the Journal
Download
[This article belongs to Volume - 25, Issue - 5]
International Medical Journal
Journal ID
:
IMJ-24-04-2020-441
Total View
:
265
Title
:
Relation between orexin A and obesity in coronary heart patients
Abstract
: The research included estimation of orexin-A level in coronary heart patients and compared it with control group. The results demonstrate that the normal mean of orexin A in serum control group was (344. 47± 6.51 pg/mol) for both sexes and ages range between (20-more of 50) year and there was a significant decline in orexin A level in patients compared to control group. Also, orexin A level was not affected by age and sex. Obese and overweight individuals have significant decrease in hormone level than the normal and underweight. The clinical parameter showed a significant decrease in adiponectin and HDL-C concentration in patients compared to control group. While there was a significant increase in insulin, glucose, total cholesterol, triglyceride concentration, HOMA-IR and atherogenic index in patients compared to control. Study the correlation coefficients of orexin A with some clinical parameters showed a significant negative correlation of orexin A with glucose, total cholesterol, triglyceride concentration and atherogenic index in control and patients group and with insulin and HOMA-IR in patients. Also, there was a significant positive correlation with concentration of adiponectin and HDL-C in control and patients group and with insulin in control group. It was concluded that Orexin A has a protective effect against CHD and low level of Orexin A increases risk of CHD. Moreover, there is a relation between orexin A and obesity, orexin A protect against obesity, and the level of orexin A could be used as a marker for CHD and obesity
Download Info
×
Paper Access Key
Access Key
Submit
No Access Key (
Request for Download
)
Name
Email
Country
Send Request
Our Certificates
Guidelines
Information For Authors
Information Editorial Board
FAQ
Further Information
Article Processing Charges
Open Access Policy
Terms and Conditions
Privacy Policy
User Feedback