Vol - 25, Issue - 2
About the Journal
[This article belongs to Volume - 25, Issue - 2]
International Medical Journal
Journal ID : IMJ-06-02-2020-215
Total View : 262

Abstract : Stable coronary heart disease is the highest cause of death. This situation involves neutrophils and lymphocytes described by the neutrophil lymphocyte ratio (NLR) in inflammation. Inflammation makes an increase in acute phase protein C-reactive protein (CRP) and serum amyloid A (SAA), both of which also play a role in coronary artery stenosis. The degree of stenosis is measured by Gensini scores through invasive angiography. The relationship between the three hematological parameters and the degree of coronary artery stenosis needs a further investigation. A cross sectional study involving 35 stable coronary heart patients was calculated according to the formula of the sample size with inclusion and exclusion criteria. Examination of NLR was done by comparing absolute neutrophil counts, moreover absolute lymphocytes was examined by using a hematology analyzer. CRP levels were examined by the hs-CRP method and SAA levels were examined by using the ELISA principle. The Gensini score was used to assess coronary artery stenosis. The Spearman relationship test was used to analyze between variables. p <0.05 was considered significant. There is a significant positive relationship between NLR and SAA but no correlation between CRP and NLR and SAA. There is a significant positive relationship between NLR and SAA with Gensini scores. There is no relationship between CRP and Gensini score. NLR is a simple parameter and SAA is a biomolecular parameter, both of which increase with increasing weight coronary artery stenosis, in stable CHD patients, it can be used for evaluation of stable CHD patients

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