Abstract : The neck is a wide anatomical area. The swellings in neck can be caused by innumerable pathological lesions arising from the various anatomical structures lying therein. Neck masses have proven to be a diagnostic dilemma to physicians since time immemorial. High-resolution USG is the initial imaging investigation for neck masses in most of the cases. CT has proven to be the most useful imaging modality available in an assessment of lesions of head and neck. The present study was an observational prospective study which was carried out in department of Radio-diagnosis at tertiary care hospital to study the role of USG and MDCT in the evaluation of neck masses. A total of 50 patients were included in the study. after taking written informed consent from each patient and Ethical approval from Ethics committee of institution. In the present study, the average age was found to be 84.9 years with a maximum number of patients between 51 to 60 years. The youngest patient in our study was aged 5 years and the oldest patient was 83 years old. USG and CT ensure accurate anatomical localization, characterization, aspiration, cytology, planning of biopsy in benign lesions. In malignant tumors, these are useful and provide essential information about the tumor extent that directly affects the surgical approach necessary for curative resection. Evaluation with USG and CT allows radiologists to make a substantial contribution to the diagnosis and management of patients presenting with neck masses. Careful analysis of imaging features of a neck mass in combination with clinical history and physical examination produce a reasonably short differential diagnosis in every case. USG and CT are considered complementary modalities for imaging neck masses in adults. CT has obvious advantages over USG in neck imaging like better soft tissue resolution, bone evaluation and deeper soft tissue evaluation.