Abstract : This study objective to emphasize the value of ultrasound technique in estimating and evaluating characterization features of renal failure in Sudanese patients in order to increase public awareness toward renal failure and its consequences. Ninety-six hemodialysis Sudanese participants were diagnosed having renal failure disease and being evaluated and followed up by Ultrasound techniques. The inclusion criteria were retrieved and patients having other renal pathologies or patient less than 20 years old were excluded. Demographic results regarding gender distribution revealed that male was being affected slightly more than female (52.1%), with male: female ratio of (1.1). Age group (20-30) years had the higher prevalence with (24 %). Most of the obtained sample were married with (65.6%). Clinical etiology achieved that (42.7%) had hypertension followed with (33.3%) had diabetes. (83.3%) had chronic end stage renal failure. Regarding sonographic outcomes estimations; (55.2%) had normal kidney during ultrasound, while (51%) had increased parenchymal echogenicity and (57.3%) had poor cortico /medullary differentiation. The study proved that ultrasound technique is accurate in detecting and estimating the characterization of renal failure. Also, the study emphasizes the importance of regular follow-up of patients in hemodialysis by ultrasound technique to assess their condition and improve the way of treatment