Abstract : This study is conducted to compare the Space occupying lesions of liver its demographic, clinical, imaging & cytopathological correlations & further treatment measures in our institute. Prospective observational study was conducted in our institute from 2019 to October 2021 following approval from ethical committee of hospital. Both Male & Female with all age group patients were included in the study. Mean age of 50 study was 47.36% with highest 53 years & lowest 36years. There were 38(76%) male & 12 (24%)female. 46%were Hepatic abscess, most common lesion of liver followed by metastatic lesions of liver 24%. SOL was most common in 4th & 5th decade. USG was sensitive in all the SOLs but CT was more specific. As per our study, we inferred that abscess was most common space occupying lesion of liver for which ultrasonography was not only diagnostic but also therapeutic, as well in simple hepatic cyst & hydatid cyst. CECT was able to differentiate between Simple hepatic cyst & Multiple liver abscess from Multiple metastatic liver lesions. Hepatic Abscess, Simple Hepatic cyst were 47% managed conservatively. While Hydatid cyst Pigtail was treatment modality.