Abstract : This study was done to study the morbidity and mortality associated with SIRS and MODS in the patients’ intraabdominal infections due to various causes, traumatic and nontraumatic. This study was a prospective observational study done in a tertiary medical college in central India from 1st June 2015 to November 2017 on 200 patients admitted in surgery ward or trauma unit. In our study the Observed morbidity rate as per SIRS score 0-4 in relation to etiology was maximum i.e. 30.76% in acute pancreatitis, Mortality rate as per SIRS score 0 – 4 is found to be 0% in all etiological groups. Mortality rate as per SIRS score 5 – 8 is maximum i.e. 6.67% in intestinal obstruction/gangrene. The Morbidity rate as per MODS score 0-6 is maximum i.e. 60% in intestinal obstruction/gangrene. The Mortality rate as per MODS score 19-24 was 100% in acute pancreatitis, intestinal obstruction, ruptured liver abscess, splenic and mesenteric injury.