Abstract : Cervical cancer is one of the major life threatening malignancies in women which can be prevented in the majority of the cases. It is the commonest malignancy causing mortality among women in developing countries. In India every year about 2.2 lakh women are diagnosed with cervical cancer and about half of them succumb to it. To study the incidence of different types epithelial lesions on pap smear in postmenopausal women. A two year retrospective study was carried out in Department of Pathology, in a tertiary care hospital of south India. All postmenopausal women with clinical symptoms were included in the study. known case of malignancy were excluded from the study. Out of 455 cases found to be satisfactory cellularity 57% cases showed epithelial abnormalities with predominance of non specific inflammation with 21% followed by 15% of LSIL and 10.5% of HSIL which will most often leads to carcinoma. Five cases were diagnosed with squamous cell carcinoma and two cases with adenocarcinoma. PAP smear is the most feasible, cost effective, non invasive diagnostic modality which helps in early detection of malignancy.