Vol - 25, Issue - 3
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[This article belongs to Volume - 25, Issue - 3]
International Medical Journal
Journal ID : IMJ-13-02-2020-246
Total View : 130
Title : The Efficacy of Topical Interferon Alpha-2b in Refractory Limbal Vernal Keratoconjunctivitis: A case report

Abstract : A 20-year-old man was referred to our cornea clinic with the chief complaints of itching and photophobia in eyes and foreign body sensation, redness, and ptosis in a both eyes. He had a 10-year history of gradually enlarging limbal gelatinous masses on both eyes, which according to the other signs and impression cytology (IC) was diagnosed as a VKC. As the disease in his left eye was more severe and persistent with maximum topical steroid usage, we started the topical IFN-∝2b eye drops, that a rapid therapeutic response was observed. After three months of using the topical IFN-∝2b all ocular surface inflammation and other symptoms rapidly disappeared and we continued this drug till another 3 months, at 12-months follow-up, there was no recurrence of the limbal papillary hypertrophic lesions and other signs and symptoms of VKC. In a refractory VKC, topical IFN-∝2b can be used and enhance remission in such complex cases and can resolve patients complains rapidly
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