Abstract : Topical phenytoin, due to its positive effects in healing of ulcers has been widely used in managing Diabetic ulcer foot in current practice. Aim of this study to evaluate the efficacy of topical phenytoin in DM foot ulcers in terms of reduction in wound surface area, rate of granulation tissue formation and number of days required for healing. All diabetic ulcer foot patients after the debridement the initial size of the ulcer and presence of granulation tissue were measured and twice daily dressings were done for each patient. The wounds were reassessed on 14th day. The measurements were recorded and compared with the initial size. The difference between the Study group and Control group in terms of no of days of hospital stay, increased rate of granulation tissue, wound surface area, which is statistically significant. Topical phenytoin dressings are more effective than conventional povidone iodine and saline dressing in terms of faster reduction in wound surface area, increased rate of granulation tissue formation and lesser number days taken for wound healing.