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Vol - 28, Issue - 01
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[This article belongs to Volume - 28, Issue - 01]
International Medical Journal
Journal ID
:
IMJ-29-12-2020-708
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354
Title
:
The Expression of interleukin-15 in muscle-effect of exercise on High-Fed-Diet mice
Abstract
: This study investigates the effects of exercise on expression of interleukin-15 (IL-15) in muscle of high- fat-diet mice. Mice were divided into 5 groups of 4 in each. Apart from normal control, HFD and standard, mice also received exercise once per week, three times per week, and five times per week for 2 weeks. The expression of IL-15 was evaluated using PCR. The exercise treatment was decreasing the body weight compare with HFD group only. Furthermore, the evaluation of PCR showed that the expression of IL-15 was decreased in muscle of HFD group. However, exercise elevated the expression of IL-15. This study indicated that exercise-induced an increase of IL-15 expression following endurance exercise might be a potent mediator in obese disease.
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