Abstract : Ankylosing Spondylitis is a chronic inflammatory rheumatic disease with various extra-articular manifestations such as uveitis, renal, cardiac, and pulmonary manifestations. A cross-sectional study was conducted at the Rheumatology Unit in Baghdad Teaching Hospital, during the period from September 2018 to March 2019. Patients who had Ankylosing spondylitis were enrolled in the study. Renal ultrasonography was performed for all participants. Renal stone was observed in 10% of patients. Disease duration was significantly higher in patients with renal stone than those without renal stone (P = 0.0001). Both BASDAI and BASFI scores were significantly higher in Ankylosing Spondylitis patients with renal stone compared to those without renal stone (P = 0.0001). There was no significant difference in terms of serum calcium, ESR level and therapeutic features between patients with renal stone and those without stone. Renal stones were found to exist in AS patients. Ankylosing Spondylitis patients with long disease duration and higher values of BASDAI and BASFI scores are more susceptible to renal stones.