Abstract : Teratozoospermia is characterized by the presence of spermatozoa with abnormal morphology in sperm. Globozoospermia is a rare (incidence 0.1%) and severe form of teratozoospermia characterized by the presence in the ejaculate of a large majority of round spermatozoa without acrosome. Globozoospermia is most commonly caused by mutations in the DPY19L2 gene. Globozoospermic spermatozoa are thus unable to adhere and to penetrate the zona pellucida, causing primary infertility. The results: total teratospermia 100% (globospermia 89% and other forms of abnormal morphology 11%), necrosospermia 69%, astenozospemia 99%. The case presented is the first to be published as a pathology of infertility in the Republic of Kosovo. Teratozospermia in the form of Globozoospermia was 89%, and we called it Globospermia severe or Globospermia type III, based on the results of 100% atypical morphology (89% globospermia + 11% other atypical forms) and Necrosospermia 69% as well as Asthenzospermia 99 %.