Abstract : Early detection of COVID 19 is necessary as it has caused increased global mortality along with a variety of manifestations and rapid progression. There are many markers of COVID 19 viral pneumonia but the exist a few predictors of its severity. To observe the prevalence and importance of Eosinopenia and Lymphopenia in predicting severity of COVID-19 cases. The current study involved 81 cases of COVID 19 viral pneumonia of which 40 were classified as mild while 41 were severe requiring ICU care. The relatability between the lymphocyte and eosinophil count of the admitted patients, for severity and outcome of the disease was analysed using statistical analysis software. Among the study participants, 41 were severe cases which required ICU care and 40 were mild cases which required ward care. Out of the 41 severe cases, all 41 patients (100%) were found to have eosinopenia while 28 patients (68.3%) were found to have lymphopenia. Additionally, among the severe cases, 28 patients (68.3%) were found to have both eosinopenia and lymphopenia. A significant association was also found between lymphopenia and Acute Kidney Injury. A significant association was also observed between the presence of eosinopenia, lymphopenia and both simultaneously, and mechanical ventilation. In this study it was found that eosinopenia and lymphopenia can be considered as a marker of severity of COVID 19, thus if admission sample of Complete blood count shows eosinopenia or lymphopenia, such patients must be given vigorous treatment as probability of worsening of clinical condition is higher.