Abstract : Obesity is more common in middle age especially after menopause because of hormonal imbalance and it is also followed by estrogen depletion affecting the pelvic floor muscle. Obesity is associated with functional limitation in muscle performance such as mobility, strength, and balance and reduced functional performance and further may lead to functional disability if it is not treated with appropriate measures at a specific duration. Hence, this study aims to know the effect of stabilization and strengthening of the core and pelvic floor muscles among obese postmenopausal women. A comparative study was done for 50 post-menopausal females using a convenient sampling method from Thiruvarur were chosen. They were then divided into two groups, Group A(N=25): Proprioceptive Neuromuscular Facilitation of core and pelvic floor muscles. Group B(N=25): Swiss ball training of core and pelvic floor muscles and followed up for 12 weeks. The pre-test and post-test values were assessed for One minute sit-up test- Core muscle & Pelvic floor distress inventory [PFDI-20]- Pelvic floor muscles (urinary distress inventory) There was significant difference in the One-minute sit-up test- Core muscle & Pelvic floor distress inventory [PFDI-20]- Pelvic floor muscles (urinary distress inventory) between 2 groups with p<0.05 in improving quality of life. A (PNF) had a better prognosis than the group -B (SWIS BALL) in terms of 1 min sit – up and PFDI scores. Hence PNF exercises play a key role in stabilization and strengthening of the core and pelvic floor muscles among obese postmenopausal women