International Medical Journal (ISSN:13412051)

Aim and Scope

Aim-

International Medical Journal ISSN: (13412051) is an international open-access journal publishes twelve times each year. The "International Medical Journal" is a peer-reviewed, monthly, online international research journal, which publishes original articles, research articles, review articles with top-level work from all areas of Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody, ENT etc. Researchers in all Medical Science and Pharmacy fields are encouraged to contribute articles based on recent research. Journal publishes research articles and reviews within the whole field of Medical Science and Pharmacy Research, and it will continue to provide information on the latest trends and developments in this ever-expanding subject. International Medical Journal journal covers almost all disciplines of Medical Science and Pharmacy. Researchers and students of M.B.B.S, M.D., D.T.C.D., GYNE., M.S., M.Pharma, And PhD are requested to send their original research articles to International Medical Journal. Azerbaijan Medical Journal Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology

Scope-

International Medical Journal ISSN: (13412051) is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Anatomy Physiology Biochemistry Pharmacology
Pathology Forensic medicine Microbiology Community Medicine
Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology
Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases
Anaesthesia Cancer research Neurosurgery Orthopedics

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Latest Journals
International Medical Journal
Journal ID : IMJ-13-06-2020-502
Total View : 372

Abstract : To determine the age-related incidence and lymphocytic infiltration (both peri-tumoral & intra-tumoral) in biopsies of patients with follicular adenoma and papillary carcinoma thyroid. MATERIALS AND METHODS: A total number of 50 patients presenting with follicular adenoma and papillary thyroid carcinoma (PTC) were selected for the present study. RESULTS: Among n=25 cases of follicular adenoma (n=19), 76.0% were females and (n=6) 24.0% were males and a female to male ratio was 3.1: 1. While among n=25 cases of papillary carcinoma (n=18), 72.0% were females, and (n=7) 28.0% were males and a female to male ratio was 2.1:1. This shows a female predominance in both groups. The ages of patients were divided into three age groups; Group 1(G I, 10-34 years), Group 2 (G II, 35-59 years) & Group 3 (G III, 60-84 years). The frequency of follicular adenoma and papillary carcinoma was related to age groups by applying Fisher’s Exact Test. The statistical relation of follicular adenoma and papillary carcinoma with age was found to be significant (p= 0.046). This shows young age preponderance in follicular adenoma; while in papillary carcinoma; a greater number of cases was present in 60-84 age groups. All of the biopsy sections were examined thoroughly under the microscope to observe the lymphocytic infiltrate (both intra-tumoural and peri-tumoural) within the histological section. When this lymphocytic infiltrate was graded according to the density, it depicted a higher frequency of papillary carcinomas showing a marked degree of lymphocytic infiltrate while the majority of follicular adenomas showed a moderate degree of lymphocytic infiltrate. CONCLUSION: The majority of follicular adenomas showed a moderate degree of lymphocytic infiltrate. The density of peri-tumoral & intra-tumoral lymphocytic infiltrate varies with transition from benign to malignant tumour. It might be an independent prognostic factor if studied on a comparatively large sample size with follow up of the patients.
Full article
International Medical Journal
Journal ID : IMJ-10-06-2020-501
Total View : 252

Abstract : Cardiac Rhabdomyomas are the most common benign cardiac tumours of infancy. They are often associated with Tuberous Sclerosis Complex (TSC). Familial TSC has got about 95% penetrance. Being characterized by cutaneous stigmata in the form of facial angiofibromas, adenoma sebaceum and ashleaf macules, they are easily diagnosed in the clinical scenario. Neonatal tuberous sclerosis is not so commonly diagnosed from cutaneous stigmata. Occult TSC can be retrospectively diagnosed based on echocardiographic findings of cardiac rhabdomyomas in infants. This case report is an example of one rare case where maternal and neonatal tuberous sclerosis was diagnosed retrospectively after the diagnosis of fetal cardiac rhabdomyoma on level II ultrasound and subsequent confirmation on echocardiography. Presenly baby is asymptomatic and is planned for conservative management and follow-up.
Full article
International Medical Journal
Journal ID : IMJ-09-06-2020-500
Total View : 335

Abstract : Vitamin D deficiency and mentality dysfunction are common in low Glomerular Filtration Rate GFR in dialysis and non-dialysis patients, low level of vitamin D most lyrelated to hypertension, neurocognetionimperment, muscle weakness, hyperlipidemic, diabetes, and cardiovascular disease. Mentality domains impairment remains undiagnosed and undermanaged in chronic kidney disease CKD patients. The level of vitamin D clinically estimated by scaling the vitamin D status which is determined clinically by measuring the 25(OH)D vitamin level that circulating within body. Levels of vitamin D ranging within 30-80 ng/ml are considered optimum level, vitamin D level which evaluated as a suboptimal is further classified into deficiency and insufficiency where the susceptible to develop CKD at vitamin D deficiency. Low level of vitamin D associated with mentality dysfunction especially in hemodialysis patients but the link is still not completely cleared. Assess mentality domains defectiveness using one validated score: monumental state examination in patients with low GFR, with or without hemodialysis. A total of 63 patients with no dialysis CKD and 68 patients on scheduled hemodialysis have been included in this study in which CKD was defined as GFR<60 ml/min using MDRD equation. Exclusion criteria: <20 years, pregnant women, deaf patients, low education, and CVA patients. Mentality test have been done for all patients (CKD and ESRD) by using monumental state examination test which measures mentality (mentality) functions with a components of orientation, attention, recall, and language with score >24 (out of 30). Vitamin 25(OH) D-level assessed from each subject using enzyme immunoassay method with assay range from 40-110 ng/ml. for dialysis patients 36.8% had different 25(OH) D-level, while 40.2% had insufficient level, and 22.8 had sufficient vitamin D level. Serum level of 25(OH)D-level was significantly lower in patients on dialysis compared with CKD patients. Minimental status examination score was lower significantly in hemodialysis patients compared to non-dialysis patient. There was significant correlation between various mentality domains test (MMs) and vitamin D levels. there was high prevalence of 25 (OH) D deficiencies in patients with low GFR especially on hemodialysis associated with poor mentality domains.
Full article
International Medical Journal
Journal ID : IMJ-09-06-2020-499
Total View : 232

Abstract : intensive treatment of adult patients with acute lymphocytic leukemia in adults (ALL) by Asparaginase(LASP/PEGASP) was significantly improved patient outcomes. However, much less information available about asparaginase use and toxicity in adult in comparison with its effect in pediatric populations. This was retrospective descriptive study for 56 leukemia patients fromNasseriahgovernoratetreated by PEG-ASP according to UKALL XIprotocol, between January 2015 and October 2019. The Hb, WBCs count, Blastocyte percent., Absolute Neutrophil Count ANC, platelet count, survival rate,transplantation, chemotherapy regimen, duration, type of asparginase,phase, time from last ASP, events, presentation, recovery and dose, were considered and evaluated. 56 patients with ALL were retrospectively enrolled in this study at median age of 30 years. Males represented 60.7 % compared to 39.3 % females. The majority of patients 14(93%) were in phase I and the remaining in phase II.The best dose frequency was three doses that were enough for 8 patients (54%).10 of 15 patients (67%) did not undergo a transplant, while the remaining did not have to.Finally, 10 patients (67%) were survived and three of them with weakness.15(25%) of 56 patients were suffered from the following complications:CVST 5(33%), DVT 4(27%), Hyperglycemia 3(20%), and 1(7%) patient appeared with pancreatitis, biochemical pancreatitis, andskin rash. also, those patients presented with: seizure 5(33%), swelling 3(20%), polyurea 2(13%) and 1(7%) patient suffering polydipsia, abdominal pain, vomiting, redness, and pain. PEG-ASP is feasible as part of an intensive multiagent therapeutic regimen for adult with ALL. This regimen appears associated with improved outcomes,but there are differences in overall survival of those patients sufferingcomplications and those don’t.
Full article
International Medical Journal
Journal ID : IMJ-09-06-2020-498
Total View : 350

Abstract : A considerable alveolar bone loss occurs follows tooth extraction, this bone resorption can compromise dental implant procedure, for this reason, the concept of socket preservation techniques was introduced, in which different materials placed into the extraction socket immediately after extraction to minimize alveolar bone loss. To evaluate the effects of autologous platelets poor plasma (PPP) and autologous platelets rich plasma (PRP) on the preservation of alveolar width in extraction socket with buccal dehiscence, and to evaluate the effect of PPP and PRP on the number of osteoblasts in the newly formed bone. Six adult pointer dogs were selected for this study, after flap reflection 3mm buccal dehiscence was created with trephine bur. Then the mandibular third premolar was extracted bilaterally. The extraction sites were randomly assigned to three groups: platelets poor plasma, platelets rich plasma and control. The experiment was designed to permit the examination of the extraction site after one and two months. the alveolar width measured histomorphometrically at three level that located at 1mm, 2mm and 3mm respectively from the top of the alveolar crest. The number of osteoblasts was calculated under the microscope in six fields representing the center of the extraction socket. There was no statistically significant difference in the alveolar width between all groups, regarding the osteoblast number it was significantly higher in the PRP group after one month but not after two months. While the number of osteoblasts in the PPP group was not significantly higher after one and two months. PRP and PPP may not adequately preserve the alveolar width after implantation of these materials in the extraction socket with buccal dehiscence. At the cellular level, PRP increased the number of osteoblasts in extraction site at 1 month. At later times there was no significant difference in the number of osteoblasts in the PRP and non-PRP graft.
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