International Medical Journal

Journal ID : IMJ-27-02-2020-294

Total View : 99

Title : Evaluation of Shear Bond Strength to Human Teeth and Microhardness of GIC Containing Titanium Nano Particles: An In-Vitro Study

Abstract : This study focussed on evaluation of the addition of titanium dioxide (TiO2) nanoparticlesto conventional glass-ionomer (GC Universal Restorative Cement 2) on Vickers microhardness and shearbond strength. This study was an in-vitro experimental study. This study was carried out at Pakistan Instituteof Engineering and Applied Sciences (PIEAS). It was completed in two and half months i.e from 1stJanuary,2019 till 15 March,2019. Titania nano particles were added in conventional glass-ionomer (GCUniversal Restorative Cement 2) at 3%, 5% (w/w). Unblended powder was used as control group (Group 1)while glass-ionomer containing titania nano particles at 3% (w/w) was considered as (Group 2) and glass–ionomer containing titania nano particles at 5% (w/w) was considered as (Group 3). Diamond indentor wasused to measure surface microhardness. Cylinders of all groups (9.5X1mm) were prepared. Total of 9sample cylinders were prepared. Shear bond strength was measured using universal testing machine. Humananterior teeth were used to measure shear bond strength. Blocks of all three groups (4X4X1mm) wereattached to treated enamel and dentin surfaces. Total of 18 human anterior teeth were used to measure shearbond strength, 6 teeth for each group (3 for enamel and 3 for dentin). SEM analysis of specimen of flexuralstrength test was done before and after test. One-way ANOVA analysis was conducted to compare the shearbond strength and microhardness between the three groups. Post-hoc Tukey analysis was used to compareinter-group mean differences. An arbitrary significance value of 0.05 was considered to be significant. Alldata was entered and analysed using SPSS v 23.0. Results showed significant increase in microhardness(p<0.05) and significant increase in shear bond strength (p<0.05). Conclusions: GI-containing 3% and 5%(w/w) TiO2 nanoparticles are restorative material with enhanced mechanical properties. This interestingexperimental Glass-ionomer may be used for higher stress-bearing area restorations such as Class I and II.
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International Medical Journal

Journal ID : IMJ-27-02-2020-293

Total View : 113

Title : Diagnostic Role of Contrast Enhanced Computed Tomography (CECT) in Detecting Nodal Metastasis in Patients with Oral Squamous Cell Carcinoma Taking Histopathology as Gold Standard

Abstract : Nodal metastasis is fairly common in Oral Squamous Cell Carcinoma and is hard to detect on physical examination. Thus, a cheap and reliable method for detection of lymph node metastasis is required. The objective of current study was to evaluate the sensitivity, specificity and diagnostic accuracy of contrast enhanced computed tomography (CECT) in detecting nodal metastasis in oral squamous cell carcinoma taking histopathology as gold standard. This cross sectional study comprised of n=125 diagnosed cases of oral squamous cell carcinoma. Preoperative CECT was done in each patient. Lymph nodes showing one or more features on CECT scan including ill-defined irregular bordered mass, non-enhancing mass in the nodal area greater than 1.5 cm for sub-mandibular & jugulodigastric nodes, greater than 0.8cm for retropharyngeal nodes, greater than 1.0 cm for all other nodes, grouping of 3 or more nodes in 6-15 mm area, central necrosis evidence with decrease density and/or dirty fat appearance with extra nodal spread were considered positive. At surgery lymph nodes were removed and diagnosed for oral squamous cell carcinoma metastasis on histopathology. Topographical correlation between dissected nodes and CECT scans was performed. Out of n=125 patients, n=89 (71.2%) patients were males and n=36 (28.8%) patients were females. The male to female ratio was 2.5:1. Mean age of the patients was found to be 53.61 ±16.72. Tongue was found to be the most common site of involvement with n=34 (27.2%) cases followed by buccal mucosa n=27 (21.6%) cases. It was found that the overall sensitivity of CECT scan was 77.97%, specificity 68.18%, positive predictive value (PPV) 68.66%, negative predictive value (NPV) 77.59% and the diagnostic accuracy of CECT scan was 72.8% taking histopathology as gold standard. CECT scan was found to have acceptable diagnostic accuracy and can be a helpful tool in detecting lymph node metastasis in Oral Squamous Cell Carcinoma.
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International Medical Journal

Journal ID : IMJ-27-02-2020-291

Total View : 161

Title : Biomarkers to Identify Bacterial Coinfection in Children with Adenovirus-related Pneumonia

Abstract : We evaluate the diagnostic values of some biomarkers in detecting bacterial coinfection among 40 children with Adenovirus-related severe pneumonia. Interleukin (IL)-6, high-sensitivity C-reactive protein (hs-CRP) tests were conducted. Receiver operating characteristic (ROC) analysis was used to evaluate their diagnostic values. Study findings showed that 9 children had bacterial coinfections (22.5%). The area under the curves was 0.772, 0.696 and 0.575 for PCT, hs-CRP and IL-6, respectively. The optimal cut-off point for PCT was > 2.25 ng/ml (sensitivity 77%, specificity 40%), hs-CRP was > 51.6 mg/dl (sensitivity 50%, specificity 93%), and IL-6 was > 3.36 pg/ml (sensitivity 100%, specificity 31%).
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International Medical Journal

Journal ID : IMJ-26-02-2020-287

Total View : 137

Title : Evaluation of the impact of three-dimensional modeling on surgical decision making in patients with infratemporal and parapharyngeal tumors using CT scan and MRI

Abstract : Due to the fact that correct adoption of surgical approach in head and neck surgery is basically the ultimate goal of surgery, performing 2D and 3D modeling using MRI and CT scanning can lead to correct election of surgical approach and increase diagnosis. The purpose of this study was to use high-resolution CT scan and MRI slices to create 2D and 3D models of head and neck using 3D Slicer software in patients undergoing infratemporal and parapharyngeal tumors, and to compare the effect of 3D modeling. We also aimed to compare the effect of 3D versus 2D modeling in patients undergoing surgery and to evaluate the performance of experienced surgical staff in surgical procedure and tumor type diagnosis based on 3D model. The present case-series study was performed on 10 consecutive patients undergoing surgery for infratemporal and parapharyngeal tumors. A 3D-model consisting separate CT scans or MRI images of the head and neck areas was made. We used 3D Slicer software to reconstruct the anatomical atlas of the head and neck structure and specific tissues we want to extract from CT scans and MRI images. There was no significant difference between the type of tumor identified according to the surgeon's opinion for each patient before and after viewing the images. There was a significant difference before and after reviewing the reconstructed images of the patients according to the surgeons' viewpoints with regard to vascular and neural involvements. Examining the images effectively and significantly influences the choice of surgical approach independent to the experience of surgeons. The use of 2D and 3D modeling on imaging techniques is effective in choosing surgical approach of patients with infratemporal and parapharyngeal tumors.
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International Medical Journal

Journal ID : IMJ-25-02-2020-286

Total View : 126

Title : Challenges in Diagnosis of Pulmonary Embolism in Pulmonary Hypertension patient related to Chronic Kidney Disease

Abstract : Chronic Kidney Disease is associated with higher incidence of venous thromboembolism, including pulmonary embolism, and increased risk of morbidity and mortality. Study also showed the evidence of pulmonary hypertension related to chronic kidney disease is an independent predictor of mortality. Diagnosis of pulmonary embolism itself is challenging, especially in many comorbidities with similar features, as in pulmonary embolism or pulmonary hypertension complicated with chronic kidney disease. Multiple team approach could be necessary to improve patient evaluation and help clinical decisionmaking in order to provide the best possible care. The availability of many imaging modalities with special characteristics and accuracy can better help the diagnosis challenges.
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It is our great pleasure to announce to tie up a new bonding with a new correspondence: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery.

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International Medical Journal

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Submission Deadline ( Vol 30 , Issue 06 )
20 Jun 2023

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Publish On ( Vol 30 , Issue 05 )
31 May 2023