: Inter-trochanteric fractures are commonly reported, which are associated with considerable morbidity and mortality. Most of these fractures are unstable and require fixation. Dynamic hip screw (DHS) and Proximal Femur Nailing (PFN) have been widely accepted for this purpose, but they have always had numerous complications. There are conflicting results regarding the advantage of one of these two methods over the other. The aim of this study is to compare PFN with DSH insertion to treat intertrochanteric fracture. This double-blind clinical trial study was performed on 38 patients undergoing intertrochanteric fracture in ValiAsr hospital of Arak. We divided patients in 2 groups including proximal femoral nailing and dynamic hip screw. We check wound healing by clinical observation (2, 5 and 15 hours after surgery) and emboli (3 weeks after surgery). We recorded fracture improvement by Radiological examination after 15 days, 1, 3, 6 and 12 months after surgery. Mortality rate was recorded 6 months after surgery and lower limb movement 5 months after surgery. Data was analyzed by SPSS software 20. Duration of admission, mortality, fracture improvement (1 year after surgery) and lower limb movement were not found to be significantly different among two group (p>0.05). Duration of suture removal was shorter in DHS surgery group (p=0.012). Furthermore, wound healing in second day after surgery were not significantly different in two groups (p=0.348). In the PFN group, wound healing was found to be better (p=0.002). Our findings indicated that wound healing was better on the fifth day after surgery in the PFN group. In addition, the duration of suturing was longer in the DHS surgery group.